Evidence map›Paper›PMID 29021300›Full record

ArticleClinical and vaccine immunology : CVI2017

High-Resolution Epitope Positioning of a Large Collection of Neutralizing and Nonneutralizing Single-Domain Antibodies on the Enzymatic and Binding Subunits of Ricin Toxin.

David J Vance, Jacqueline M Tremblay, Yinghui Rong, Siva Krishna Angalakurthi, David B Volkin, C Russell Middaugh, David D Weis, Charles B Shoemaker, Nicholas J Mantis

Abstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. B Cell Epitope Mapping by High-Density Competition ELISAs.Methods in molecular biology (Clifton, N.J.) · 2025
    Article
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  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

David J VanceDivision of Infectious Disease, Wadsworth Center, New York State Department of Health, Albany, New York, USA david.vance@health.ny.gov nicholas.mantis@health.ny.gov.ORCID http://orcid.org/0000-0002-9913-7722
Jacqueline M TremblayDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA.
Yinghui RongDivision of Infectious Disease, Wadsworth Center, New York State Department of Health, Albany, New York, USA.
Siva Krishna AngalakurthiDepartment of Pharmaceutical Chemistry, Macromolecule and Vaccine Stabilization Center, University of Kansas, Lawrence, Kansas, USA.
David B VolkinDepartment of Pharmaceutical Chemistry, Macromolecule and Vaccine Stabilization Center, University of Kansas, Lawrence, Kansas, USA.
C Russell MiddaughDepartment of Pharmaceutical Chemistry, Macromolecule and Vaccine Stabilization Center, University of Kansas, Lawrence, Kansas, USA.
David D WeisDepartment of Chemistry, University of Kansas, Lawrence, Kansas, USA.
Charles B ShoemakerDepartment of Infectious Disease and Global Health, Tufts Cummings School of Veterinary Medicine, North Grafton, Massachusetts, USA.
Nicholas J MantisDivision of Infectious Disease, Wadsworth Center, New York State Department of Health, Albany, New York, USA david.vance@health.ny.gov nicholas.mantis@health.ny.gov.ORCID http://orcid.org/0000-0002-5083-8640

Funding

NIAID NIH HHS HHSN272201400021C
6 · The paper itself

Abstract

We previously produced a heavy-chain-only antibody (Ab) VH domain (V

Indexed as

Epitope MappingAnimalsAntibodies, NeutralizingCamelids, New WorldChemical Warfare AgentsEpitopesProtein BindingRicinSingle-Domain AntibodiesAntibodies, NeutralizingChemical Warfare AgentsEpitopesRicinSingle-Domain Antibodiesantibodybiodefenseepitopeneutralizingtoxinsvaccines

Identifiers

PMID29021300
PMCPMC5717184

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.