Observational studyJournal of the American Heart Association2017
Cardiometabolic Risk Variables in Preadolescent Children: A Factor Analysis.
Observational study in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Asthma and high-intensity interval training have no effect on clustered cardiometabolic risk or arterial stiffness in adolescents.European journal of applied physiology · 2021Trial
- Analysis of the Relationship of Glycated Hemoglobin with Subclinical Atherosclerosis and Arterial Stiffness in Non-Diabetic Patients: A Retrospective Study.Journal of clinical medicine · 2026Article
- Adverse Cardiometabolic Impacts of Sleep Fragmentation and Estradiol Suppression: An Experimental Model of Menopause.The Journal of clinical endocrinology and metabolism · 2026Article
- The Adverse Influence of Maternal Glycaemia During Pregnancy on Offspring's Cardiometabolic Health Profiles.Acta paediatrica (Oslo, Norway : 1992) · 2025Article
- Childhood obesity: The threatening apprentice of the adiposity empire.Reviews in endocrine & metabolic disorders · 2025Review
- Observational
- Cardiometabolic risk factor clustering in persons with spinal cord injury: A principal component analysis approach.The journal of spinal cord medicine · 2024Article
- Protocol for a Study Investigating Context-Specific Sedentary Behaviors and Cardiometabolic Health in College-Based Young Adults (CONTEXT-SB).Research square · 2024Article
- A Cross-Sectional Investigation of Preadolescent Cardiometabolic Health: Associations with Fitness, Physical Activity, Sedentary Behavior, Nutrition, and Sleep.Children (Basel, Switzerland) · 2023Article
- Inflammation subtypes in psychosis and their relationships with genetic risk for psychiatric and cardiometabolic disorders.Brain, behavior, & immunity - health · 2022Article
- A mediation analysis on the relationship between dietary glycemic load, obesity and cardiovascular risk factors in children.International journal of obesity (2005) · 2022Article
- A Systematic Review of the Long-Term Trajectory of Hemodynamics and Body Composition in Childhood Obesity.Cureus · 2021Review
- Associations of midchildhood to early adolescence central adiposity gain with cardiometabolic health in early adolescence.Obesity (Silver Spring, Md.) · 2021Article
- Analysis of Risk Factors in Patients with Subclinical Atherosclerosis and Increased Cardiovascular Risk Using Factor Analysis.Diagnostics (Basel, Switzerland) · 2021Article
- CARDIOMETABOLIC RISK AMONG MONTENEGRIN URBAN CHILDREN IN RELATION TO OBESITY AND GENDER.Acta clinica Croatica · 2021Article
- Social Jetlag and Cardiometabolic Risk in Preadolescent Children.Frontiers in cardiovascular medicine · 2021Article
- Factor analysis for the clustering of cardiometabolic risk factors and sedentary behavior, a cross-sectional study.PloS one · 2020Article
- Cardiometabolic Risk Variables in Preadolescent Children: A Factor Analysis.Journal of the American Heart Association · 2017Observational
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAtherosclerosis begins during preadolescence and is occurring at an accelerated rate. This acceleration has been linked to poor lifestyle behaviors and subsequent cardiometabolic complications. Although the clustering of cardiometabolic risk factors has been recognized for over 2 decades, previous studies in children have predominantly examined the relationships between atherosclerosis and individual cardiometabolic risk factors or have grouped together preadolescent and adolescent children. Further, no known studies have included glycated hemoglobin or central hemodynamic measures such as central systolic blood pressure and augmentation index. METHODS AND
resultsPrincipal component analysis was performed on a cross-sectional sample of 392 children (aged 9.5 years, 50% girls) from 3 representative sample sites across New Zealand. Four factors explained 60% of the variance in the measured variables. In order of variance explained, the factors were: blood pressure (central systolic blood pressure and peripheral systolic and diastolic blood pressure), adiposity (waist circumference, body mass index, and glycated hemoglobin), lipids (total cholesterol, low-density lipoprotein cholesterol, and high-density lipoprotein cholesterol), and vascular (augmentation index, heart rate, and fasting blood glucose).
conclusionsIn accordance with previous findings in adults and adolescents, one common factor is unlikely to define cardiometabolic health in preadolescent children. Each of the factors, except vascular, which was predominantly explained by augmentation index, are in agreement with previous findings in adolescents. An additional novel finding was that glycated hemoglobin and fasting blood glucose loaded onto different factors, supporting previous work suggesting that fasting blood glucose indicates short-term glycemic control, whereas glycated hemoglobin reflects chronic glycemic control. CLINICAL
trial registrationURL: www.anzctr.org.au/. ID: ACTRN12614000433606.
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