Evidence map›Paper›PMID 29021274›Full record

Observational studyJournal of the American Heart Association2017

Prevalence and Outcomes of Left-Sided Valvular Heart Disease Associated With Chronic Kidney Disease.

Zainab Samad, Joseph A Sivak, Matthew Phelan, Phillip J Schulte, Uptal Patel, Eric J Velazquez

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Journal of the American Heart Association, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 118 citations in OpenAlex.

  1. Article
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  3. Non-contrastEuropean heart journal. Case reports · 2026
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Zainab SamadDivision of Cardiology, Department of Medicine, Duke University, Durham, NC zainab.samad@dm.duke.edu.
Joseph A SivakDivision of Cardiology, Department of Medicine, Duke University, Durham, NC.
Matthew PhelanDuke Clinical Research Institute, Duke University, Durham, NC.
Phillip J SchulteDepartment of Biostatistics, Mayo Clinic, Rochester, MN.
Uptal PatelDuke Clinical Research Institute, Duke University, Durham, NC.
Eric J VelazquezDivision of Cardiology, Department of Medicine, Duke University, Durham, NC.
Duke University · USClinical Research Institute · USMayo Clinic · US

Funding

Renal Genomics CoreP30DK096493 · NIDDK · DUKE UNIVERSITY · PI FOSTER, MARY H., SVETKEY, LAURA P · 2012 to 2016
$5.9M
NIDDK NIH HHS P30 DK096493
6 · The paper itself

Abstract

backgroundChronic kidney disease (CKD) is an adverse prognostic marker for valve intervention patients; however, the prevalence and related outcomes of valvular heart disease in CKD patients is unknown. METHODS AND

resultsIncluded patients underwent echocardiography (1999-2013), had serum creatinine values within 6 months before index echocardiogram, and had no history of valve surgery. CKD was defined as diagnosis based on the

conclusionsPrevalence of at least mild AS and MR is substantially higher and is associated with significantly lower survival among patients with versus without CKD. There is significant interaction among CKD, AS/MR severity, and mortality, with increasingly worse outcomes for CKD patients with increasing AS/MR severity.

Indexed as

AdultAgedAged, 80 and overAge FactorsAortic ValveAortic Valve StenosisComorbidityDatabases, FactualEchocardiographyFemaleGlomerular Filtration RateHumansKaplan-Meier EstimateKidneyMaleMiddle Agedaortic stenosischronic kidney diseaseechocardiographymitral regurgitationmortality

Identifiers

PMID29021274
PMCPMC5721834
OpenAlexW2762376901

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.