Evidence map›Paper›PMID 29021243›Full record

ArticleGenes & development2017

Zucchini-dependent piRNA processing is triggered by recruitment to the cytoplasmic processing machinery.

Alicia K Rogers, Kathy Situ, Edward M Perkins, Katalin Fejes Toth

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 49 citations in OpenAlex.

  1. Review
  2. Review
  3. In thebioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Regulatory roles of PIWI-interacting RNAs in cardiovascular disease.American journal of physiology. Heart and circulatory physiology · 2025
    Review
  7. How germ granules promote germ cell fate.Nature reviews. Genetics · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Review
  15. Article
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  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alicia K RogersDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
Kathy SituDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
Edward M PerkinsDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
Katalin Fejes TothDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
California Institute of Technology · US

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
DROSOPHILA GENOMICS RESOURCE CENTERP40OD010949 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Andrew Zelhof · 2012 to 2026
$9.4M
Understanding the mechanism of Piwi-induced transcriptional silencingR01GM110217 · NIGMS · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI FEJES TOTH, KATALIN · 2014 to 2024
$3.1M
NIGMS NIH HHS R01 GM110217NIH HHS P40 OD010949NIH HHS P40 OD018537
6 · The paper itself

Abstract

The piRNA pathway represses transposable elements in the gonads and thereby plays a vital role in protecting the integrity of germline genomes of animals. Mature piRNAs are processed from longer transcripts, piRNA precursors (pre-piRNAs). In

Indexed as

RNA Processing, Post-TranscriptionalAnimalsArgonaute ProteinsCytoplasmDrosophila melanogasterDrosophila ProteinsEndoribonucleasesFemaleGerm CellsOvaryPeptide Initiation FactorsRNA HelicasesRNA PrecursorsRNA, Small InterferingAGO3 protein, DrosophilaArgonaute Proteinsarmi protein, Drosophilaaub protein, DrosophilaDrosophila ProteinsEndoribonucleasesPeptide Initiation Factorspiwi protein, DrosophilaRNA HelicasesRNA PrecursorsRNA, Small InterferingZuc protein, DrosophilanuagepiRNA biogenesisPiwiRNA sequestrationtetheringZucchini

Identifiers

PMID29021243
PMCPMC5695087
OpenAlexW2762018119

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.