Evidence map›Paper›PMID 29021156›Full record

ArticleJournal of clinical microbiology2017

Safety and Accuracy of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of Highly Pathogenic Organisms.

James T Rudrik, Marty K Soehnlen, Michael J Perry, Maureen M Sullivan, Wanda Reiter-Kintz, Philip A Lee, Denise Pettit, Anthony Tran, Erin Swaney

Open access · hybridAbstract readEvaluation StudyMulticenter Study
In one paragraph

Article in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 64 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. International journal of microbiology · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. BMJ case reports · 2020
    Article
  12. Article
  13. Review
  14. Article
  15. Human Melioidosis.Clinical microbiology reviews · 2020
    Review
  16. Journal of clinical microbiology · 2020
    Article
  17. Article
  18. MALDI-MS: Emerging roles in pathology and laboratory medicine.Clinical mass spectrometry (Del Mar, Calif.) · 2019
    Review
  19. Article
  20. Answer to March 2019 Photo Quiz.Journal of clinical microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 1 country.

James T RudrikBureau of Laboratories, Michigan Department of Health and Human Services, Lansing, Michigan, USA.
Marty K SoehnlenBureau of Laboratories, Michigan Department of Health and Human Services, Lansing, Michigan, USA soehnlenm@michigan.gov.
Michael J PerryBiodefense Laboratory, Wadsworth Center, New York State Department of Health, Albany, New York, USA.
Maureen M SullivanPublic Health Laboratory, Minnesota Department of Health, St. Paul, Minnesota, USA.
Wanda Reiter-KintzState Hygienic Laboratory at the University of Iowa, Coralville, Iowa, USA.
Philip A LeeBureau of Public Health Laboratories, Florida Department of Health, Jacksonville, Florida, USA.
Denise PettitNorth Carolina State Laboratory of Public Health, North Carolina Department of Health and Human Services, Raleigh, North Carolina, USA.
Anthony TranBureau of the Public Health Laboratory, New York City Department of Health and Mental Hygiene, New York City, New York, USA.
Erin SwaneyTexas Department of State Health Services Laboratory, Austin, Texas, USA.
Michigan Department of Health and Human Services · USFlorida Department of Health · USMinnesota Department of Health · USNC Department of Health and Human Services · USNew York City Department of Health and Mental Hygiene · USNew York State Department of Health · USTexas Department of State Health Services · USUniversity of Iowa · US

Funding

OSELS CDC HHS U60 OE000103
6 · The paper itself

Abstract

Matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) sample preparation methods, including the direct, on-plate formic acid, and ethanol/formic acid tube extraction methods, were evaluated for their ability to render highly pathogenic organisms nonviable and safe for handling in a biosafety level 2 laboratory. Of these, the tube extraction procedure was the most successful, with none of the tested strains surviving this sample preparation method. Tube extracts from several agents of bioterrorism and their near neighbors were analyzed in an eight-laboratory study to examine the utility of the Bruker Biotyper and Vitek MS MALDI-TOF MS systems and their

Indexed as

Microbial ViabilityBacteriaBacteriological TechniquesHumansOccupational ExposureSpecimen HandlingSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionizationbiothreat agentsclinical laboratoryMALDI-TOFpathogenic organismspublic health

Identifiers

PMID29021156
PMCPMC5703816
OpenAlexW2761617288

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.