Evidence map›Paper›PMID 29021107›Full record

ArticleJournal of substance abuse treatment2017

Marijuana use and HIV treatment outcomes among PWH receiving care at an urban HIV clinic.

Sagarika Sinha, Mary E McCaul, Heidi E Hutton, Anne K Monroe, Anika Alvanzo, Catherine Lesko, Bryan Lau, Jeanne Keruly, Richard D Moore, Geetanjali Chander

Open access · greenAbstract read
In one paragraph

Article in Journal of substance abuse treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Sagarika SinhaUniversity of Maryland School of Medicine, United States.
Mary E McCaulJohns Hopkins University School of Medicine, United States.
Heidi E HuttonJohns Hopkins University School of Medicine, United States.
Anne K MonroeJohns Hopkins University School of Medicine, United States.
Anika AlvanzoJohns Hopkins University School of Medicine, United States.
Catherine LeskoJohns Hopkins University, Bloomberg School of Public Health, United States.
Bryan LauJohns Hopkins University, Bloomberg School of Public Health, United States.
Jeanne KerulyJohns Hopkins University School of Medicine, United States.
Richard D MooreJohns Hopkins University School of Medicine, United States.
Geetanjali ChanderJohns Hopkins University School of Medicine, United States. Electronic address: gchande1@jhmi.edu.
Johns Hopkins University · USJohns Hopkins Medicine · USUniversity of Maryland, Baltimore · US

Funding

Vaccine Response and Immunotherapeutics SWGP30AI094189 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Richard E. Chaisson · 2012 to 2026
$67.0M
North American AIDS Cohorts on Collaboration and Design (NAACCORD)U01AI069918 · NIAID · JOHNS HOPKINS UNIVERSITY · PI Keri Nicole Althoff, RICHARD Douglas MOORE · 2006 to 2026
$65.2M
Johns Hopkins HIV Clinical CohortU01DA036935 · NIDA · JOHNS HOPKINS UNIVERSITY · PI MOORE, RICHARD DOUGLAS · 2014 to 2024
$14.9M
3/4 Alcohol Research Consortium in HIV - Epidemiological Research Arm (ARCH-ERA)U01AA020793 · NIAAA · UNIVERSITY OF WASHINGTON · PI CRANE, HEIDI M., LAU, BRYAN · 2011 to 2020
$5.8M
1/4 Alcohol Research Consortium in HIV-Administrative Core (ARCH-AC)U24AA020801 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI CHANDER, GEETANJALI, MCCAUL, MARY E · 2011 to 2021
$3.5M
NIAAA NIH HHS U01 AA020793NIAAA NIH HHS U24 AA020801NIAID NIH HHS P30 AI094189NIAID NIH HHS U01 AI069918NIDA NIH HHS U01 DA036935
6 · The paper itself

Abstract

backgroundWhile marijuana use is prevalent among persons with HIV (PWH), few studies have examined the relationship between marijuana use and HIV treatment outcomes independent of alcohol and other drug use.

methodsWe conducted a prospective cohort study to examine the relationships between frequency of marijuana use and antiretroviral therapy (ART) adherence and viral suppression in patients enrolled in the Johns Hopkins HIV Clinical Cohort between September 2013 through November 2015 (N=1377). We categorized marijuana use as no use, none in the last 3months, monthly use or less, weekly/daily. Our outcomes of interest were use of ART, ≥90 ART adherence, and viral suppression (HIV1-RNA<200 copies). We conducted multivariable analyses to examine associations between the frequency of marijuana use and our treatment outcomes, using generalized estimating equations to account for repeated measures. Other independent variables of interest included alcohol use, other drug use, and depressive symptoms. Analyses were adjusted for age, race, sex and HIV acquisition risk factor.

resultsIn multivariable analyses we found no statistically significant association between frequency of marijuana use and our treatment outcomes. Alcohol use, other drug use and depressive symptoms were associated with lower odds of ART adherence and viral suppression.

conclusionsIn this sample of PWH in care, frequency of marijuana use independent of other substance use does not appear to be associated with negative HIV treatment outcomes. Our results indicate that unlike alcohol, other substances and depression, marijuana use may not be a barrier to the effective treatment of HIV.

Indexed as

Marijuana UseMedication AdherenceAnti-Retroviral AgentsFemaleHIV InfectionsHumansMaleMiddle AgedProspective StudiesTreatment OutcomeUrban PopulationViral LoadAnti-Retroviral AgentsAdherenceHIVMarijuanaViral suppression

Identifiers

PMID29021107
PMCPMC5935451
OpenAlexW2753975959

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.