Evidence map›Paper›PMID 29020990›Full record

ArticleActa veterinaria Scandinavica2017

A comparison of two different anthelmintic treatment regimens against natural gastrointestinal nematode infections on two Lithuanian sheep farms.

Tomas Kupcinskas, Inga Stadaliene, Algimantas Paulauskas, Pavelas Trusevicius, Saulius Petkevicius, Johan Höglund, Mindaugas Sarkunas

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta veterinaria Scandinavica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Tomas KupcinskasDepartment of Veterinary Pathobiology, Veterinary Academy, Lithuanian University of Health Sciences, Tilzės str. 18, 47181, Kaunas, Lithuania.
Inga StadalieneDepartment of Veterinary Pathobiology, Veterinary Academy, Lithuanian University of Health Sciences, Tilzės str. 18, 47181, Kaunas, Lithuania.
Algimantas PaulauskasFaculty of Natural Sciences, Department of Biology, Vytautas Magnus University, 44404, Kaunas, Lithuania.
Pavelas TruseviciusBuivydiskiai Veterinary Clinic, Kliniku str. 1, Buivydiskių k., 14165, Vilnius, Lithuania.
Saulius PetkeviciusDepartment of Veterinary Pathobiology, Veterinary Academy, Lithuanian University of Health Sciences, Tilzės str. 18, 47181, Kaunas, Lithuania. saulius.petkevicius@lsmuni.lt.
Johan HöglundDepartment of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Section for Parasitology, Box 7036, 750 07, Uppsala, Sweden.
Mindaugas SarkunasDepartment of Veterinary Pathobiology, Veterinary Academy, Lithuanian University of Health Sciences, Tilzės str. 18, 47181, Kaunas, Lithuania.
Lithuanian University of Health Sciences · LTSwedish University of Agricultural Sciences · SEVytautas Magnus University · LT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccording to targeted treatment (TT), the whole flock is dewormed based on knowledge of the risk, or parameters that quantify the mean level of infection, whereas according to targeted selective treatment (TST), only individual animals within the grazing group are treated, based on parasitological, production and/or morbidity parameters. The aim of this study was to compare two different treatment protocols on sheep farms in Lithuania. The study was conducted from 15 April to 31 October 2014 on three sheep farms. On the TT (the whole flock) and T(S)T (with FECs ≥ 300, respectively) farms all adult animals were treated orally with fenbendazole irrespective of EPG counts before the grazing season. The second treatment was applied with injectable ivermectin on both farms. However, on the TT farm all sheep were also treated on 2nd August regardless of their EPG counts, while on the T(S)T farm only those animals with an EPG ≥ 300 were treated on 1 July using a threshold of ≥ 300 EPG. No treatments were administered on the control farm (n = 1) during the study.

resultsSpring treatment of ewes significantly reduced nematode faecal egg counts (FEC) both on the TT and T(S)T farms, with the benefit of lowering pasture contamination with infective L

conclusionsThe results of this study show that both treatment strategies were useful in reducing clinical effects (BCS and DS) of gastrointestinal nematode parasitism and increasing the performance in lambs. Furthermore, on the T(S)T farm some of animals were left in refugia, helping to slow down the development of anthelmintic resistance (AR) in future.

Indexed as

Administration, OralAnimalsAnthelminticsDrug Administration ScheduleFemaleFenbendazoleGastrointestinal DiseasesInjections, SubcutaneousIvermectinLithuaniaNematode InfectionsSheepSheep DiseasesAnthelminticsFenbendazoleIvermectinAnthelmintic resistanceNematodeSheepTargeted selective treatmentTargeted treatment

Identifiers

PMID29020990
PMCPMC5637350
OpenAlexW2762990153

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.