Evidence map›Paper›PMID 29020222›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2018

Antimicrobial Resistance Gene Acquisition and Depletion Following Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection.

Victor Leung, Caroline Vincent, Thaddeus J Edens, Mark Miller, Amee R Manges

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.

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  8. FMT alleviates multidrug-resistantFrontiers in microbiology · 2026
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Victor LeungDepartment of Pathology and Laboratory Medicine, University of British Columbia, Vancouver.
Caroline VincentDepartment of Microbiology and Immunology, McGill University, Montréal, Québec.
Thaddeus J EdensDevil's Staircase Consulting, West Vancouver, British Columbia.
Mark MillerMcGill University, Montréal, Québec.
Amee R MangesSchool of Population and Public Health, University of British Columbia.
McGill University · CAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fecal microbiota transplantation (FMT) may be a novel approach to eliminate multidrug-resistant bacteria from the gut and to prevent future infections. Using whole metagenome sequencing data from 8 FMT donor-recipient pairs, we identified 37 and 95 antimicrobial resistance genes that were acquired by or removed from FMT recipients, respectively.

Indexed as

Gastrointestinal MicrobiomeGenes, MDRAnti-Bacterial AgentsClostridium InfectionsDrug Resistance, Multiple, BacterialFecal Microbiota TransplantationFecesGenes, BacterialHigh-Throughput Nucleotide SequencingHumansRecurrenceAnti-Bacterial Agentsantimicrobial resistanceClostridium difficile infectionfecal microbiota transplantationmetagenomicsmultidrug resistance

Identifiers

PMID29020222
PMCPMC5850035
OpenAlexW2754916606

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.