Evidence map›Paper›PMID 2902004›Full record

ArticleImmunogenetics1988

Genotyping chickens for the B-G subregion of the major histocompatibility complex using restriction fragment length polymorphisms.

M M Miller, H Abplanalp, R Goto

Abstract read
PubMed Publisher
In one paragraph

Article in Immunogenetics, 1988. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 68 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. BG1 has a major role in MHC-linked resistance to malignant lymphoma in the chicken.Proceedings of the National Academy of Sciences of the United States of America · 2009
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Immunoglobulin variable-region-like domains of diverse sequence within the major histocompatibility complex of the chicken.Proceedings of the National Academy of Sciences of the United States of America · 1991
    Article
  16. Genetic organization of the chicken MHC.Immunologic research · 1990
    Review
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

M M MillerDepartment of Molecular Biochemistry, Beckman Research Institute, City of Hope, Duarte, CA 91010.
H Abplanalp
R Goto
City Of Hope National Medical Center · USUniversity of California, Davis · US

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI STANLEY R. HAMILTON · 1985 to 2026
$86.3M
IMMUNOBIOLOGY OF THE MAJOR HISTOCOMPATIBILITY COMPLEXR01AI021736 · NIAID · CITY OF HOPE NATIONAL MEDICAL CENTER · PI MILLER, MARCIA M · 1985 to 1991
–
NCI NIH HHS CA33572NIAID NIH HHS AI21736
6 · The paper itself

Abstract

Chicken B-G-subregion cDNA probes were used to analyze restriction fragment length polymorphisms (RFLP) of the B-G subregion of the chicken major histocompatibility complex. Genomic DNA from chickens representing 17 of the 27 standard B haplotypes were digested with restriction endonucleases and analyzed in Southern hybridizations with two cDNA clones from the B-G subregion. Each B-G genotype was found to produce a unique pattern of restriction fragments in these Southern hybridizations. With 15 of the 17 genotypes examined, the different genotypes could be readily distinguished in hybridizations produced with DNA digested with a single restriction enzyme, PVU II. The two additional genotypes produced nearly identical patterns in PVU II preparations and with three additional enzymes as well, but were readily distinguishable in Eco RI digestions. For many of the haplotypes, samples from several individuals in different flocks were examined. In every instance, genotyping by RFLP pattern was found to confirm the B-G allele assigned serologically.

Indexed as

Major Histocompatibility ComplexAnimalsBlotting, SouthernChickensDNA ProbesHaplotypesPolymorphism, Restriction Fragment LengthDNA Probes

Identifiers

PMID2902004
OpenAlexW2033481827

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.