ArticleMolecules (Basel, Switzerland)2017
Pratol, an O-Methylated Flavone, Induces Melanogenesis in B16F10 Melanoma Cells via p-p38 and p-JNK Upregulation.
Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 36 citations in OpenAlex.
- Skin-Whitening Effects of Cannabinol (CBN) Through Melanin Inhibition in B16F10 Melanoma Cells.International journal of molecular sciences · 2025Article
- Multi-omics and network pharmacology reveal Huayu-Tongbi decoction reduced arthritis-related bone erosion.Chinese medicine · 2025Article
- Piperine Regulates Melanogenesis through ERK Activation and Proteasomal Degradation of MITF.Biomolecules & therapeutics · 2025Article
- The Pathogenesis of Oxidative Stress-Induced Chloasma and Its Therapeutic Implications.Clinical, cosmetic and investigational dermatology · 2025Review
- Quercetin 3-O-(6″-O-E-caffeoyl)-β-D-glucopyranoside, a Flavonoid Compound, Promotes Melanogenesis through the Upregulation of MAPKs and Akt/GSK3β/β-Catenin Signaling Pathways.International journal of molecular sciences · 2023Article
- Imperatorin Positively Regulates Melanogenesis through Signaling Pathways Involving PKA/CREB, ERK, AKT, and GSK3β/β-Catenin.Molecules (Basel, Switzerland) · 2022Article
- Anti-Inflammatory Effects of Psoralen Derivatives on RAW264.7 Cells via Regulation of the NF-κB and MAPK Signaling Pathways.International journal of molecular sciences · 2022Article
- Mechanistic Insights into the Ameliorating Effect of Melanogenesis of Psoralen Derivatives in B16F10 Melanoma Cells.Molecules (Basel, Switzerland) · 2022Article
- Calycosin, a Common Dietary Isoflavonoid, Suppresses Melanogenesis through the Downregulation of PKA/CREB and p38 MAPK Signaling Pathways.International journal of molecular sciences · 2022Article
- Grape Extract Promoted α-MSH-Induced Melanogenesis in B16F10 Melanoma Cells, Which Was Inverse to Resveratrol.Molecules (Basel, Switzerland) · 2021Article
- Anti-Inflammatory Effects of 6-Methylcoumarin in LPS-Stimulated RAW 264.7 Macrophages via Regulation of MAPK and NF-κB Signaling Pathways.Molecules (Basel, Switzerland) · 2021Article
- Jeju Magma-Seawater Inhibits α-MSH-Induced Melanogenesis via CaMKKβ-AMPK Signaling Pathways in B16F10 Melanoma Cells.Marine drugs · 2020Article
- Emerging Strategies to Protect the Skin from Ultraviolet Rays Using Plant-Derived Materials.Antioxidants (Basel, Switzerland) · 2020Review
- JNK suppresses melanogenesis by interfering with CREB-regulated transcription coactivator 3-dependent MITF expression.Theranostics · 2020Article
- Tobramycin Promotes Melanogenesis by Upregulating p38 MAPK Protein Phosphorylation in B16F10 Melanoma Cells.Antibiotics (Basel, Switzerland) · 2019Article
- Liquiritin and Liquiritigenin Induce Melanogenesis via Enhancement of p38 and PKA Signaling Pathways.Medicines (Basel, Switzerland) · 2019Article
- Identification of Anti-Melanogenesis Constituents fromMolecules (Basel, Switzerland) · 2018Article
- Melanogenesis Inhibitory Activity, Chemical Components and Molecular Docking Studies ofJournal of evidence-based integrative medicineArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tyrosinase is the rate-limiting enzyme critical for melanin synthesis. It controls pigmentation in the skin. Activation of tyrosinase is currently the most common approach in the development of tanning and haircare products. Pratol is a 7-hydroxy-4-methoxyflavone found in
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.