ArticleAmerican journal of public health2017
Recreational Cannabis Legalization and Opioid-Related Deaths in Colorado, 2000-2015.
Article in American journal of public health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Association between state cannabis laws and opioid outcomes: A systematic review.Drug and alcohol dependence · 2026Pooled it
- Causal effects of cannabis legalization on parents, parenting, and children: A systematic review.Preventive medicine · 2022Pooled it
- Pooled it
- Impact evaluations of drug decriminalisation and legal regulation on drug use, health and social harms: a systematic review.BMJ open · 2020Pooled it
- A Rapid Review of the Impact of Systems-Level Policies and Interventions on Population-Level Outcomes Related to the Opioid Epidemic, United States and Canada, 2014-2018.Public health reports (Washington, D.C. : 1974)Pooled it
- The association between state cannabis legalization and non-fatal opioid poisonings among adults with employer-sponsored insurance in the United States.Preventive medicine reports · 2026Article
- The role of prescription opioid and cannabis supply policies on opioid overdose deaths.American journal of epidemiology · 2025Article
- Cannabis Policies, Cannabis, and Opioids in Suicide and Undetermined Intent Death.American journal of preventive medicine · 2025Article
- Do Medical and Recreational Marijuana State Laws Impact Trends in Postoperative Opioid Prescriptions Among Patients Who Have Undergone TJA?Clinical orthopaedics and related research · 2025Article
- Medical Cannabis for Patients Over Age 50: A Multi-site, Prospective Study of Patterns of Use and Health Outcomes.Cannabis (Albuquerque, N.M.) · 2025Article
- The influence of transformations in supply on methamphetamine initiation among people injecting opioids in the United States.Harm reduction journal · 2024Article
- Age-related Patterns of Medical Cannabis Use: A Survey of Authorized Patients in Canada.Cannabis (Albuquerque, N.M.) · 2024Article
- Health, safety, and socioeconomic impacts of cannabis liberalization laws: An evidence and gap map.Campbell systematic reviews · 2023Article
- Adult Medical Cannabinoid Use and Changes in Prescription Controlled Substance Use.Cannabis and cannabinoid research · 2023Article
- Article
- Cannabis use to manage opioid cravings among people who use unregulated opioids during a drug toxicity crisis.The International journal on drug policy · 2023Article
- Impact of Recreational Cannabis Legalization on Opioid Prescribing and Opioid-Related Hospital Visits in Colorado: an Observational Study.Journal of general internal medicine · 2023Observational
- Use of Cannabis as a Harm Reduction Strategy Among People Who Use Drugs: A Cohort Study.Cannabis and cannabinoid research · 2023Article
- Association of a Positive Drug Screening for Cannabis With Mortality and Hospital Visits Among Veterans Affairs Enrollees Prescribed Opioids.JAMA network open · 2022Article
- APCDs can Provide Important Insights for Surveilling the Opioid Epidemic, With Caveats.Medical care research and review : MCRR · 2022Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo examine the association between Colorado's legalization of recreational cannabis use and opioid-related deaths.
methodsWe used an interrupted time-series design (2000-2015) to compare changes in level and slope of monthly opioid-related deaths before and after Colorado stores began selling recreational cannabis. We also describe the percent change in opioid-related deaths by comparing the unadjusted model-smoothed number of deaths at the end of follow-up with the number of deaths just prior to legalization.
resultsColorado's legalization of recreational cannabis sales and use resulted in a 0.7 deaths per month (b = -0.68; 95% confidence interval = -1.34, -0.03) reduction in opioid-related deaths. This reduction represents a reversal of the upward trend in opioid-related deaths in Colorado.
conclusionsLegalization of cannabis in Colorado was associated with short-term reductions in opioid-related deaths. As additional data become available, research should replicate these analyses in other states with legal recreational cannabis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.