Evidence map›Paper›PMID 29019320›Full record

ArticleeLife2017

Distinct cellular and molecular mechanisms for β3 adrenergic receptor-induced beige adipocyte formation.

Yuwei Jiang, Daniel C Berry, Jonathan M Graff

Open access · goldAbstract read
In one paragraph

Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed, 135 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Thermogenic Adipose ADH5 Counteracts Age-related Metabolic Decline.bioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Molecular Regulation of Thermogenic Mechanisms in Beige Adipocytes.International journal of molecular sciences · 2024
    Review
  18. Article
  19. Article
  20. The Role ofCells · 2024
    Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Yuwei JiangDivision of Endocrinology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, United States.ORCID 0000-0002-2132-0279
Daniel C BerryDivision of Endocrinology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, United States.ORCID 0000-0002-5200-1182
Jonathan M GraffDivision of Endocrinology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, United States.
The University of Texas Southwestern Medical Center · USCornell University · US

Funding

Biomarkers, Lineage Analysis--metabolic disease statesR01DK066556 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI GRAFF, JONATHAN M · 2003 to 2017
$5.3M
Invertebrate Models of Fat StorageR01DK064261 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI GRAFF, JONATHAN M · 2003 to 2014
$3.3M
Hormonal Regulation of Fat DepositionR01DK088220 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI GRAFF, JONATHAN M · 2010 to 2014
$2.6M
Molecular regulation of adipose tissue development, homeostasis and expansionK01DK111771 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI JIANG, YUWEI · 2016 to 2021
$705k
Regulators of the adipose tissue niche control adiposity and metabolismK01DK109027 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI BERRY, DANIEL CARL · 2016 to 2019
$570k
NIDDK NIH HHS K01 DK109027NIDDK NIH HHS K01 DK111771NIDDK NIH HHS R01 DK064261NIDDK NIH HHS R01 DK066556NIDDK NIH HHS R01 DK088220
6 · The paper itself

Abstract

Beige/brite adipocytes are induced within white adipose tissues (WAT) and, when activated, consume glucose and fatty acids to produce heat. Classically, two stimuli have been used to trigger a beiging response: cold temperatures and β3-adrenergic receptor (

Indexed as

Cell DifferentiationAdipocytes, BeigeAnimalsCold TemperatureMice, Inbred C57BLReceptors, Adrenergic, beta-1Receptors, Adrenergic, beta-3Adrb1 protein, mouseAdrb3 protein, mouseReceptors, Adrenergic, beta-1Receptors, Adrenergic, beta-3adiposebeige adipocytesbeta adrenergic receptorsBritecell biologycold exposuredevelopmental biologymouseSMAstem cells

Identifiers

PMID29019320
PMCPMC5667933
OpenAlexW2763289003

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.