Evidence map›Paper›PMID 29019307›Full record

ArticleEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin2017

Control measures following a case of imported Lassa fever from Togo, North Rhine Westphalia, Germany, 2016.

Clara Lehmann, Matthias Kochanek, Diana Abdulla, Stephan Becker, Boris Böll, Anne Bunte, Daniel Cadar, Arno Dormann, Markus Eickmann, Petra Emmerich and 25 more

Open access · diamondAbstract read
In one paragraph

Article in Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.

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  19. New Lineage of Lassa Virus, Togo, 2016.Emerging infectious diseases · 2018
    Article
  20. Lessons learnt from imported cases and onward transmission of Lassa fever in Europe support broader management of viral haemorrhagic fevers.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors at 8 institutions in 1 country.

Clara LehmannDepartment I of Internal Medicine, University of Cologne, Germany.
Matthias KochanekCentre of Integrated Oncology Köln, University of Cologne, Germany.
Diana AbdullaCentre of Integrated Oncology Köln, University of Cologne, Germany.
Stephan BeckerGerman Center for Infection Research (DZIF), Gießen-Marburg-Langen, Germany.
Boris BöllCentre of Integrated Oncology Köln, University of Cologne, Germany.
Anne BuntePublic Health Department Cologne, Germany.
Daniel CadarGerman Centre for Infection Research (DZIF), Hamburg, Germany.
Arno DormannMunicipal Hospital of Cologne, Medical Department Holweide, Germany.
Markus EickmannGerman Center for Infection Research (DZIF), Gießen-Marburg-Langen, Germany.
Petra EmmerichDepartment of Tropical Medicine and Infectious Diseases, Center of Internal Medicine II, University of Rostock, Rostock, Germany.
Torsten FeldtClinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany.
Christina FrankDepartment for Infectious Disease Epidemiology, Robert Koch Institute, Berlin, Germany.
Jochen FriesDepartment of Pathology, University of Cologne, Germany.
Martin GabrielGerman Centre for Infection Research (DZIF), Hamburg, Germany.
Udo GoetschHealth Protection Authority City of Frankfurt am Main, Germany.
René GottschalkUniversity Hospital Frankfurt, Institute of Medical Virology, Germany.
Stephan GüntherGerman Centre for Infection Research (DZIF), Hamburg, Germany.
Michael HallekCentre of Integrated Oncology Köln, University of Cologne, Germany.
Dieter HäussingerClinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany.
Christian HerzogCentre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany.
Björn JensenClinic for Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany.
Felix KolibayDepartment for Clinical Affairs, University of Cologne, Germany.
Michael KrakauMunicipal Hospital of Cologne, Medical Department Holweide, Germany.
Georg LangebartelsDepartment for Clinical Affairs, University of Cologne, Germany.
Toni RiegerGerman Centre for Infection Research (DZIF), Hamburg, Germany.
Lars SchaadeCentre for Biological Threats and Special Pathogens, Robert Koch Institute, Berlin, Germany.
Jonas Schmidt-ChanasitGerman Centre for Infection Research (DZIF), Hamburg, Germany.
Edgar SchömigClinical director University of Cologne, Germany.
Gundolf SchüttfortUniversity Hospital Frankfurt, Department of Infectious Diseases, Germany.
Alexander Shimabukuro-VornhagenCentre of Integrated Oncology Köln, University of Cologne, Germany.
Michael von Bergwelt-BaildonCentre of Integrated Oncology Köln, University of Cologne, Germany.
Ulrike WielandInstitute of Virology, University of Cologne, Germany.
Gerhard WiesmüllerPublic Health Department Cologne, Germany.
Timo WolfUniversity Hospital Frankfurt, Department of Infectious Diseases, Germany.
Gerd FätkenheuerDepartment I of Internal Medicine, University of Cologne, Germany.
University of Cologne · DEBernhard Nocht Institute for Tropical Medicine · DEGerman Center for Infection Research · DEGoethe University Frankfurt · DEHeinrich Heine University Düsseldorf · DERobert Koch Institute · DEKrankenhaus Köln-Holweide · DEUniversity of Rostock · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In a patient transferred from Togo to Cologne, Germany, Lassa fever was diagnosed 12 days post mortem. Sixty-two contacts in Cologne were categorised according to the level of exposure, and gradual infection control measures were applied. No clinical signs of Lassa virus infection or Lassa specific antibodies were observed in the 62 contacts. Thirty-three individuals had direct contact to blood, other body fluids or tissue of the patients. Notably, with standard precautions, no transmission occurred between the index patient and healthcare workers. However, one secondary infection occurred in an undertaker exposed to the corpse in Rhineland-Palatinate, who was treated on the isolation unit at the University Hospital of Frankfurt. After German authorities raised an alert regarding the imported Lassa fever case, an American healthcare worker who had cared for the index patient in Togo, and who presented with diarrhoea, vomiting and fever, was placed in isolation and medevacked to the United States. The event and the transmission of Lassa virus infection outside of Africa underlines the need for early diagnosis and use of adequate personal protection equipment (PPE), when highly contagious infections cannot be excluded. It also demonstrates that larger outbreaks can be prevented by infection control measures, including standard PPE.

Indexed as

Contact TracingTravelDisease OutbreaksGermanyHumansInfection ControlLassa FeverMaleMiddle AgedQuarantineRisk ManagementTogocontact precautionshemorrhagic feverisolationLassa feverquarantineWest Africa

Identifiers

PMID29019307
PMCPMC5709954
OpenAlexW2763349198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.