Evidence map›Paper›PMID 29019168›Full record

ReviewVirologica Sinica2017

Lipids, lipid metabolism and Kaposi's sarcoma-associated herpesvirus pathogenesis.

Lu Dai, Zhen Lin, Wei Jiang, Erik K Flemington, Zhiqiang Qin

Open access · greenAbstract readReview
In one paragraph

Review in Virologica Sinica, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Curbing Lipids: Impacts ON Cancer and Viral Infection.International journal of molecular sciences · 2019
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Lu DaiDepartment of Genetics, Louisiana State University Health Sciences Center, Louisiana Cancer Research Center, New Orleans, 70112, USA. ldai@lsuhsc.edu.ORCID http://orcid.org/0000-0002-6818-8535
Zhen LinDepartment of Pathology, Tulane University Health Sciences Center, Tulane Cancer Center, New Orleans, 70112, USA.
Wei JiangDepartment of Microbiology and Immunology, Division of Infectious Diseases, Department of Medicine, Medical University of South Carolina, Charleston, 29425, USA.
Erik K FlemingtonDepartment of Pathology, Tulane University Health Sciences Center, Tulane Cancer Center, New Orleans, 70112, USA.
Zhiqiang QinDepartment of Genetics, Louisiana State University Health Sciences Center, Louisiana Cancer Research Center, New Orleans, 70112, USA. zqin@lsuhsc.edu.ORCID http://orcid.org/0000-0002-9905-1275
Tongji University · CNTulane University · USMedical University of South Carolina · US

Funding

Tracking & Evaluation CoreU54GM104940 · NIGMS · LSU PENNINGTON BIOMEDICAL RESEARCH CTR · PI Peter Todd Katzmarzyk · 2012 to 2026
$69.1M
Translational Genomics Core (TGC)P20GM121288 · NIGMS · LSU HEALTH SCIENCES CENTER · PI Arunava Roy · 2017 to 2026
$22.4M
"Project 3" MHV68 IncRNA/miRNA interaction in latency and lympomagenesisP01CA214091 · NCI · UNIVERSITY OF FLORIDA · PI Scott A. Tibbetts · 2017 to 2026
$15.9M
Epstein Barr virus antisense transcriptionR01AI106676 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI FLEMINGTON, ERIK K · 2014 to 2018
$1.9M
Intercellular communication in Epstein Barr virus reactivationR01AI101046 · NIAID · TULANE UNIVERSITY OF LOUISIANA · PI FLEMINGTON, ERIK K · 2012 to 2016
$1.9M
Synergistic effect of HIV virions and bacterial LPS on memory B cell apoptosisR01AI091526 · NIAID · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI JIANG, WEI · 2011 to 2015
$1.4M
On the pathogenic role of anti-CD4 antibody in poor CD4+ T cell recovery after antiretroviral therapy in HIV diseaseR01AI128864 · NIAID · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI JIANG, WEI · 2017 to 2021
$1.1M
NCI NIH HHS P01 CA214091NIAID NIH HHS R01 AI091526NIAID NIH HHS R01 AI101046NIAID NIH HHS R01 AI106676NIAID NIH HHS R01 AI128864NIGMS NIH HHS P20 GM121288NIGMS NIH HHS U54 GM104940
6 · The paper itself

Abstract

Lipids are essential for mammalian cells to maintain many physiological functions. Emerging evidence has shown that cancer cells can develop specific alterations in lipid biosynthesis and metabolism to facilitate their survival and various malignant behaviors. To date, the precise role of cellular lipids and lipid metabolism in viral oncogenesis is still largely unclear with only a handful of literature covering this topic to implicate lipid metabolism in oncogenic virus associated pathogenesis. In this review, we focus on the role of lipid biosynthesis and metabolism in the pathogenesis of the Kaposi's sarcoma-associated herpesvirus, a common causative factor for cancers arising in the immunocompromised settings.

Indexed as

Herpesvirus 8, HumanHumansLipid MetabolismSarcoma, KaposiherpesvirusKaposi’s sarcoma-associated herpesvirus (KSHV)lipid metabolism

Identifiers

PMID29019168
PMCPMC5869022
OpenAlexW2764043269

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.