Evidence map›Paper›PMID 29018926›Full record

ArticleEuropean radiology2018

Optimisation of window settings for traditional and noise-optimised virtual monoenergetic imaging in dual-energy computed tomography pulmonary angiography.

Tommaso D'Angelo, Andreas M Bucher, Lukas Lenga, Christophe T Arendt, Julia L Peterke, Damiano Caruso, Silvio Mazziotti, Alfredo Blandino, Giorgio Ascenti, Ahmed E Othman and 4 more

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Article in European radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
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  7. Review
  8. The value of dual-energy computed tomography in the evaluation of myocarditisDiagnostic and interventional radiology (Ankara, Turkey) · 2023
    Article
  9. Article
  10. Dual-Energy CT of the Heart: A Review.Journal of imaging · 2022
    Review
  11. Review
  12. Article
  13. Article
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  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tommaso D'AngeloDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Andreas M BucherDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Lukas LengaDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Christophe T ArendtDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Julia L PeterkeDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Damiano CarusoDepartment of Radiological Sciences, Oncological and Pathological Sciences, "La Sapienza" University Hospital, Latina, Italy.
Silvio MazziottiDepartment of Biomedical Sciences and Morphological and Functional Imaging, "G. Martino" University Hospital Messina, Via Consolare Valeria 1, 98100, Messina, Italy.
Alfredo BlandinoDepartment of Biomedical Sciences and Morphological and Functional Imaging, "G. Martino" University Hospital Messina, Via Consolare Valeria 1, 98100, Messina, Italy.
Giorgio AscentiDepartment of Biomedical Sciences and Morphological and Functional Imaging, "G. Martino" University Hospital Messina, Via Consolare Valeria 1, 98100, Messina, Italy.
Ahmed E OthmanDepartment for Diagnostic and Interventional Radiology, Eberhard Karls University Tuebingen, University Hospital Tübingen, Tübingen, Germany.
Simon S MartinDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Doris LeithnerDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Thomas J VoglDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany.
Julian L WichmannDepartment of Diagnostic and Interventional Radiology, University Hospital Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany. docwichmann@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo define optimal window settings for displaying virtual monoenergetic images (VMI) of dual-energy CT pulmonary angiography (DE-CTPA).

methodsForty-five patients who underwent clinically-indicated third-generation dual-source DE-CTPA were retrospectively evaluated. Standard linearly-blended (M_0.6), 70-keV traditional VMI (M70), and 40-keV noise-optimised VMI (M40+) reconstructions were analysed. For M70 and M40+ datasets, the subjectively best window setting (width and level, B-W/L) was independently determined by two observers and subsequently related with pulmonary artery attenuation to calculate separate optimised values (O-W/L) using linear regression. Subjective evaluation of image quality (IQ) between W/L settings were assessed by two additional readers. Repeated measures of variance were performed to compare W/L settings and IQ indices between M_0.6, M70, and M40+.

resultsB-W/L and O-W/L for M70 were 460/140 and 450/140, and were 1100/380 and 1070/380 for M40+, respectively, differing from standard DE-CTPA W/L settings (450/100). Highest subjective scores were observed for M40+ regarding vascular contrast, embolism demarcation, and overall IQ (all p<0.001).

conclusionsApplication of O-W/L settings is beneficial to optimise subjective IQ of VMI reconstructions of DE-CTPA. A width slightly less than two times the pulmonary trunk attenuation and a level approximately of overall pulmonary vessel attenuation are recommended. KEY POINTS: • Application of standard window settings for VMI results in inferior image perception. • No significant differences between B-W/L and O-W/L for M70/M40+ were observed. • O-W/L for M70 were 450/140 and were 1070/380 for M40+. • Improved subjective IQ characteristics were observed for VMI displayed with O-W/L.

Indexed as

Computed Tomography AngiographyFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedPulmonary ArteryPulmonary EmbolismRadiography, Dual-Energy Scanned ProjectionReproducibility of ResultsRetrospective StudiesSignal-To-Noise RatioComputed tomography pulmonary angiographyDual-energy CTPulmonary embolismWindow levelWindow width

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.