ArticleCurrent genetics2018
Genetics of trehalose biosynthesis in desert-derived Aureobasidium melanogenum and role of trehalose in the adaptation of the yeast to extreme environments.
Article in Current genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 37 citations in OpenAlex.
- Pigmented fungi derived from hot and cold deserts ecosystems: taxonomy, genomic and biotechnological approach.World journal of microbiology & biotechnology · 2026Review
- Exploring the effects of excipients on complex coacervation.Journal of colloid and interface science · 2025Article
- Lessons from Extremophiles: Functional Adaptations and Genomic Innovations across the Eukaryotic Tree of Life.Genome biology and evolution · 2024Article
- Physiological characterization of polyextremotolerant yeasts from cold environments of Patagonia.Extremophiles : life under extreme conditions · 2024Article
- Transcriptomic and genomic effects of gamma-radiation exposure on strains of the black yeastMicrobiology spectrum · 2023Article
- Microbial Metabolites Beneficial to Plant Hosts Across Ecosystems.Microbial ecology · 2023Review
- Exogenous Regulators Enhance the Yield and Stress Resistance of Chlamydospores of the Biocontrol AgentJournal of fungi (Basel, Switzerland) · 2022Article
- Transcriptome analysis of Auricularia fibrillifera fruit-body responses to drought stress and rehydration.BMC genomics · 2022Article
- Integrative transcriptome analysis revealed the pathogenic molecular basis ofFrontiers in microbiology · 2022Article
- Integrative proteomic and physiological analyses of the molecular response to dessication-stress inFrontiers in plant science · 2022Article
- A Potential Fungal ProbioticJournal of fungi (Basel, Switzerland) · 2021Article
- Plant Transcriptome Reprograming and Bacterial Extracellular Metabolites Underlying Tomato Drought Resistance Triggered by a Beneficial Soil Bacteria.Metabolites · 2021Article
- The Genome-Wide Mutation Shows the Importance of Cell Wall Integrity in Growth of the Psychrophilic Yeast Metschnikowia australis W7-5 at Different Temperatures.Microbial ecology · 2021Article
- Two dominant selectable markers for genetic manipulation in Neurospora crassa.Current genetics · 2020Article
- New insight into the mechanisms protecting bacteria during desiccation.Current genetics · 2020Review
- Osmolyte-Induced Folding and Stability of Proteins: Concepts and Characterization.Iranian journal of pharmaceutical research : IJPR · 2019Review
- Polyamine Synthesis Effects Capsule Expression by Reduction of Precursors inFrontiers in microbiology · 2019Article
- Metabolome- and genome-scale model analyses for engineering ofBiotechnology for biofuels · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
Melanin plays an important role in the stress adaptation of Aureobasidium melanogenum XJ5-1 isolated from the Taklimakan desert. A trehalose-6-phosphate synthase gene (TPS1 gene) was cloned from K5, characterized, and then deleted to determine the role of trehalose in the stress adaptation of the albino mutant K5. No stress response element and heat shock element were found in the promoter of the TPS1 gene. Deletion of the TPS1 gene in the albino mutant rendered a strain DT43 unable to synthesize any trehalose, but DT43 still could grow in glucose, suggesting that its hexokinase was insensitive to inhibition by trehalose-6-phosphate. Overexpression of the TPS1 gene enhanced trehalose biosynthesis in strain ET6. DT43 could not grow at 33 °C, whereas K5, ET6, and XJ5-1 could grow well at this temperature. Compared with K5 and ET6, DT43 was highly sensitive to heat shock treatment, high oxidation, and high desiccation, but all the three strains demonstrated the same sensitivity to UV light and high NaCl concentration. Therefore, trehalose played an important role in the adaptation of K5 to heat shock treatment, high oxidation, and high desiccation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.