Evidence map›Paper›PMID 29018913›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2017

Meeting report of the 8

Andreas Friebe, Peter Sandner, Achim Schmidtko

Erratum issuedOpen access · hybridAbstract readConference Proceedings
In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Soluble Guanylate Cyclase Stimulators and Activators.Handbook of experimental pharmacology · 2021
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. cGMP Signaling and Vascular Smooth Muscle Cell Plasticity.Journal of cardiovascular development and disease · 2018
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Andreas FriebeInstitute of Physiology, University of Würzburg, Röntgenring 9, 97070, Würzburg, Germany.
Peter SandnerDrug Discovery, Bayer AG, Aprather Weg 18a, 42096, Wuppertal, Germany. peter.sandner@bayer.com.
Achim SchmidtkoInstitute of Pharmacology, College of Pharmacy, Goethe University, Max-von-Laue-Str. 9, 60438, Frankfurt, Germany.
Bayer (Germany) · DEGoethe University Frankfurt · DEUniversity of Würzburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although the Nobel Prize for the discovery of nitric oxide (NO) dates back almost 20 years now, the knowledge about cGMP signaling is still constantly increasing. It looks even so that our understanding of the role of the soluble guanylyl cyclase (sGC) and particulate guanylyl cyclase (pGC) in health and disease is in many aspects at the beginning and far from being understood. This holds even true for the therapeutic impact of innovative drugs acting on both the NO/sGC and the pGC pathways. Since cGMP, as second messenger, is involved in the pathogenesis of numerous diseases within the cardiovascular, pulmonary, renal, and endocrine systems and also plays a role in neuronal, sensory, and tumor processes, drug applications might be quite broad. On the 8th International Conference on cGMP, held in Bamberg, Germany, world leading experts came together to discuss these topics. All aspects of cGMP research from the basic understanding of cGMP signaling to clinical applicability were discussed in depth. In addition, present and future therapeutic applications of cGMP-modulating pharmacotherapy were presented ( http://www.cyclicgmp.net/index.html ).

Indexed as

AnimalsCyclic GMPGuanylate CyclaseHeart DiseasesHumansNervous System Physiological PhenomenaNitric OxideCyclic GMPGuanylate CyclaseNitric OxidecGMPGuanylyl cyclasesNatriuretic peptidesNitric oxidePhosphodiesterases

Identifiers

PMID29018913
PMCPMC5783999
OpenAlexW4229873349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.