ArticlePeerJ2017
Elevated serum osteoprotegerin may predict peripheral arterial disease after kidney transplantation: a single-center prospective cross-sectional study in Taiwan.
Article in PeerJ, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Observational
- Serum osteoprotegerin level is positively associated with peripheral artery disease in patients with peritoneal dialysis.Renal failure · 2020Article
- Serum sclerostin as an independent marker of peripheral artery disease in elderly persons.International journal of clinical and experimental pathology · 2018Article
- Serum myostatin level is a positive predictor of endothelial function measured by digital thermal monitoring of vascular reactivity in kidney transplantation patients.Tzu chi medical journalArticle
- Association of serum osteopontin with first hospitalization and all-cause mortality after kidney transplantation.Tzu chi medical journalArticle
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOsteoprotegerin (OPG) is a potential biomarker for severity and complications of cardiovascular diseases. Peripheral arterial disease (PAD) is associated with an increased risk of death in kidney transplantation (KT) patients. This prospective cross-sectional study evaluated the relationship between serum OPG and PAD in KT patients.
methodsSeventy-four KT patients were enrolled for this PAD study. Fasting blood samples were obtained to measure serum OPG levels by using enzyme-linked immunosorbent assay kits. The ankle-brachial index (ABI) of less than 0.9 was applied for PAD diagnosis.
resultsThirteen patients (17.6%) were diagnosed with PAD. Diabetes ( DISCUSSION: Exploration of reliable biomarkers for early identification of vascular risk is crucial for KT patients. Elevated serum OPG levels may predict PAD in KT patients with cutoff value of 7.117 pg/L.
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