ArticleFrontiers in immunology2017
Very Early-Onset Inflammatory Manifestations of X-Linked Chronic Granulomatous Disease.
Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- Chronic Granulomatous Disease: Clinical and Molecular Characterization of Brazilian Patients.The journal of gene medicine · 2026Article
- Clinical and genetic description of patients with chronic granulomatous disease in a pediatric hospitalBiomedica : revista del Instituto Nacional de Salud · 2024Article
- Inflammatory Complications in Chronic Granulomatous Disease.Journal of clinical medicine · 2024Review
- Molecular Challenges in the Diagnosis of X-Linked Chronic Granulomatous Disease: CNVs, Intronic Variants, Skewed X-Chromosome Inactivation, and Gonosomal Mosaicism.Journal of clinical immunology · 2023Article
- Cyba and Nox2 mutant rats show different incidences of eosinophilia in the genetic background- and sex-dependent manner.Experimental animals · 2023Article
- Neonatal Manifestations of Chronic Granulomatous Disease: MAS/HLH and Necrotizing Pneumonia as Unusual Phenotypes and Review of the Literature.Journal of clinical immunology · 2022Review
- Inborn Errors of Immunity With Fetal or Perinatal Clinical Manifestations.Frontiers in pediatrics · 2022Review
- Invasive Pulmonary Aspergillosis with Marked Eosinophilia as a Unique Presentation of Chronic Granulomatous Disease.European journal of case reports in internal medicine · 2022Article
- Clinical manifestations and genetic analysis of 4 children with chronic granulomatous disease.Medicine · 2020Observational
- Gene analysis of seven cases of primary immunodeficiency.Translational pediatrics · 2020Article
- Monogenic Inflammatory Bowel Disease: It's Never Too Late to Make a Diagnosis.Frontiers in immunology · 2020Article
- A C126RFrontiers in pediatrics · 2018Article
Corrections and comments
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Authors and funding
16 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic granulomatous disease (CGD) is a rare primary immune deficiency caused by mutations in genes coding for components of the nicotinamide adenine dinucleotide phosphate oxidase, characterized by severe and recurrent bacterial and fungal infections, together with inflammatory complications. Dysregulation of inflammatory responses are often present in this disease and may lead to granulomatous lesions, most often affecting the gastrointestinal (GI) and urinary tracts. Treatment of inflammatory complications usually includes corticosteroids, whereas antimicrobial prophylaxis is used for infection prevention. Curative treatment of both infectious susceptibility and inflammatory disease can be achieved by hematopoietic stem cell transplantation. We report herein three patients with the same mutation of the
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