ArticleFrontiers in neurology2017
Socioeconomic Outcome and Quality of Life in Adults after Status Epilepticus: A Multicenter, Longitudinal, Matched Case-Control Analysis from Germany.
Article in Frontiers in neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Pooled it
- Clinician-Reported Physical and Cognitive Impairments After Convulsive Status Epilepticus: Post Hoc Study of a Randomized Controlled Trial.Neurocritical care · 2024Trial
- DIagnostic Subdural EEG electrodes And Subdural hEmatoma (DISEASE): a study protocol for a prospective nonrandomized controlled trial.Neurological research and practice · 2020Trial
- Novel EP2 Antagonist Attenuates Microgliosis and Memory Deficits in Pilocarpine-Induced Status Epilepticus Mice.Journal of medicinal chemistry · 2026Article
- Article
- Opportunities for and Challenges of Pulmonary Drug Delivery in the Management of Acute Exacerbations of CNS Disorders.CNS drugs · 2025Review
- The impact of revised definitions on the epidemiology of status epilepticus: A population-based study.Epilepsia · 2025Article
- Review
- Status epilepticus in patients with brain tumors and metastases: A multicenter cohort study of 208 patients and literature review.Neurological research and practice · 2024Article
- Is prophylactic anti-convulsive treatment necessary in subdural hematomas?Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023Article
- Clinical characteristics and outcomes of patients with recurrent status epilepticus episodes.Neurological research and practice · 2023Article
- Acute-on-chronic subdural hematoma: a new entity for prophylactic anti-epileptic treatment?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2022Article
- Isoflurane in (Super-) Refractory Status Epilepticus: A Multicenter Evaluation.Neurocritical care · 2021Article
- [S2k guidelines: status epilepticus in adulthood : Guidelines of the German Society for Neurology].Der Nervenarzt · 2021Review
- Factors Associated With Prolonged Length of Stay in Patients Hospitalized With Generalized Convulsive Status Epilepticus in the United States.The Neurohospitalist · 2021Article
- Intranasal midazolam as first-line inhospital treatment for status epilepticus: a pharmaco-EEG cohort study.Annals of clinical and translational neurology · 2019Article
- [Acceptance, demand, reasons for consultation and outcome of counseling on epilepsy in Hesse and Lower Franconia].Der Nervenarzt · 2019Article
- Perampanel for treatment of status epilepticus in Austria, Finland, Germany, and Spain.Acta neurologica Scandinavica · 2019Article
- The Different Clinical Features Between Autoimmune and Infectious Status Epilepticus.Frontiers in neurology · 2019Article
- Long-term outcomes of status epilepticus: A critical assessment.Epilepsia · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is a lack of data concerning socioeconomic outcome and quality of life (QoL) in patients after status epilepticus (SE) in Germany. PATIENTS AND
methodsAdult patients treated between 2011 and 2015 due to SE at the university hospitals in Frankfurt, Greifswald, and Marburg were asked to fill out a questionnaire regarding long-term outcome of at least 3 months after discharge. The SE cohort consisted of 25.9% patients with an acute symptomatic, 42% with a remote symptomatic and previous epilepsy, 22.2% with a new-onset remote symptomatic, and 9.9% with other or unknown etiology. A matched case-control analysis was applied for comparison with patients with drug refractory epilepsy and seizure remission, both not previously affected by SE.
resultsA total of 81 patients (mean age: 58.7 ± 18.0 years; 58% female) participated. A non-refractory course was present in 59.3%, while 27.2% had a refractory SE (RSE) and 13.6% had a superrefractory SE (SRSE). Before admission, a favorable modified Rankin Scale (mRS) of 0-3 was found in 82.7% (67/81), deteriorating to 38.3% (31/81) ( DISCUSSION: Patients after SE show substantial impairments in their QoL and daily life activities. However, in the long term, patients with RSE and SRSE had a relatively favorable outcome comparable to that of patients with a non-refractory SE course. This underlines the need for efficient therapeutic options in SE.
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