ArticleFrontiers in molecular neuroscience2017
Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders.
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Article in Frontiers in molecular neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.
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28citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
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Who cites it
28 citing papers in PubMed, 46 citations in OpenAlex.
- Assessing Computational Strategies for the Evaluation of Antibody Binding Affinities.Journal of chemical theory and computation · 2025Article
- Connexin hemichannel blockade by abEC1.1 disrupts glioblastoma progression, suppresses invasiveness, and reduces hyperexcitability in preclinical models.Cell communication and signaling : CCS · 2025Article
- A fully human IgG1 antibody targeting connexin 32 extracellular domain blocks CMTX1 hemichannel dysfunction in an in vitro model.Cell communication and signaling : CCS · 2024Article
- Selection of Leptin Surrogates by a General Phenotypic Screening Method for Receptor Agonists.Biomolecules · 2024Article
- Spatial and Temporal Localization of Connexins in Cells Using Confocal Microscopy.Methods in molecular biology (Clifton, N.J.) · 2024Article
- A Protocol for the Automated Assessment of Cutaneous Pathology in a Mouse Model of Hemichannel Dysfunction.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Measurement of CaMethods in molecular biology (Clifton, N.J.) · 2024Article
- Generation of Connexin-Expressing Stable Cell Pools.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Connexins in epidermal health and diseases: insights into their mutations, implications, and therapeutic solutions.Frontiers in physiology · 2024Review
- Increased Hemichannel Activity Displayed by a Connexin43 Mutation Causing a Familial Connexinopathy Exhibiting Hypotrichosis with Follicular Keratosis and Hyperostosis.International journal of molecular sciences · 2023Article
- The Bioactive Phenolic Agents Diaryl Ether CVB2-61 and Diarylheptanoid CVB4-57 as Connexin Hemichannel Blockers.Pharmaceuticals (Basel, Switzerland) · 2022Article
- In Silico Maturation of a Nanomolar Antibody against the Human CXCR2.Biomolecules · 2022Article
- A Quantitative Assay for CaInternational journal of molecular sciences · 2022Article
- Pathological mechanisms of connexin26-related hearing loss: Potassium recycling, ATP-calcium signaling, or energy supply?Frontiers in molecular neuroscience · 2022Review
- Cellular mechanisms of connexin-based inherited diseases.Trends in cell biology · 2022Review
- Failure Of Hearing Acquisition in Mice With Reduced Expression of Connexin 26 Correlates With the Abnormal Phasing of Apoptosis Relative to Autophagy and Defective ATP-Dependent CaFrontiers in cellular neuroscience · 2022Article
- Connexin hemichannel inhibition ameliorates epidermal pathology in a mouse model of keratitis ichthyosis deafness syndrome.Scientific reports · 2021Article
- Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.Nature communications · 2021Article
- Connexin hemichannel inhibition improves skin pathology in Clouston syndrome mice.EBioMedicine · 2020Article
- A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice.EBioMedicine · 2020Article
Corrections and comments
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Authors and funding
28 authors at 8 institutions in 3 countries.
Liang XuShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
Andrea CarrerCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Francesco ZontaShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
Zhihu QuShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
Peixiang MaShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
Sheng LiShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
Federico CerianiCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Damiano BurattoCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Giulia CrispinoCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Veronica ZorziCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Gaia ZiraldoCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Francesca BrunoDepartment of Physics and Astronomy "G. Galilei,", University of PadovaPadova, Italy.
Chiara NardinCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Chiara PeresCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Flavia MazzardaCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Anna M SalvatoreCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Marcello RaspaCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Ferdinando ScavizziCNR Institute of Cell Biology and NeurobiologyMonterotondo, Italy.
Youjun ChuShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
Sichun XieShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
Xuemei YangSchool of Life Science and Technology, Shanghai Tech UniversityShanghai, China.
Jun LiaoSchool of Life Science and Technology, Shanghai Tech UniversityShanghai, China.
Xiao LiuShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
Wei WangShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
Shanshan WangShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
Guang YangShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
Richard A LernerDepartment of Cell and Molecular Biology, The Scripps Research InstituteLa Jolla, CA, United States.
Fabio MammanoShanghai Institute for Advanced Immunochemical Studies, ShanghaiTech UniversityShanghai, China.
ShanghaiTech University · CNInstitute of Cell Biology and Neurobiology · ITUniversity of Padua · ITRoma Tre University · ITUniversità Cattolica del Sacro Cuore · ITChinese Academy of Sciences · CNScripps Research Institute · USVeneto Institute of Molecular Medicine · IT
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
antibody libraryantibody structurecochleaconnexinsepitope identificationkeratinocytessyndromic autosomal hereditary deafness
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.