Evidence map›Paper›PMID 29018242›Full record

ArticleScientific reports2017

Nuclear factor (erythroid derived 2)-like 2 activation increases exercise endurance capacity via redox modulation in skeletal muscles.

Sechang Oh, Shoichi Komine, Eiji Warabi, Kentaro Akiyama, Akiko Ishii, Kazunori Ishige, Yuji Mizokami, Keisuke Kuga, Masaki Horie, Yoshihiro Miwa and 3 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 69 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 1 country.

Sechang OhThe Center of Sports Medicine and Health Sciences, Tsukuba University Hospital, Tsukuba, Ibaraki, 305-8576, Japan.
Shoichi KomineThe Center of Sports Medicine and Health Sciences, Tsukuba University Hospital, Tsukuba, Ibaraki, 305-8576, Japan.
Eiji WarabiFaculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan.
Kentaro AkiyamaFaculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan.
Akiko IshiiFaculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan.
Kazunori IshigeFaculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan.
Yuji MizokamiFaculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan.
Keisuke KugaFaculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan.
Masaki HorieFaculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan.
Yoshihiro MiwaFaculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, 305-8575, Japan.
Takao IwawakiDepartment of Life Science, Medical Research Institute, Kanazawa Medical University, Uchinada, Kahoku, Ishikawa, 920-0293, Japan.
Masayuki YamamotoDepartment of Medical Biochemistry, Tohoku University Graduate School of Medicine, Sendai, Miyagi, 980-8575, Japan.
Junichi ShodaThe Center of Sports Medicine and Health Sciences, Tsukuba University Hospital, Tsukuba, Ibaraki, 305-8576, Japan. shodaj@md.tsukuba.ac.jp.
University of Tsukuba · JPJapan Society for the Promotion of Science · JPKanazawa Medical University · JPTohoku University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sulforaphane (SFN) plays an important role in preventing oxidative stress by activating the nuclear factor (erythroid derived 2)-like 2 (Nrf2) signalling pathway. SFN may improve exercise endurance capacity by counteracting oxidative stress-induced damage during exercise. We assessed running ability based on an exhaustive treadmill test (progressive-continuous all-out) and examined the expression of markers for oxidative stress and muscle damage. Twelve- to 13-week-old Male wild-type mice (Nrf2

Indexed as

Physical EnduranceAdenosine TriphosphatasesAnimalsEnergy MetabolismGlutathioneIsothiocyanatesLuciferasesLuminescenceMaleMice, Inbred C57BLMitochondriaMuscle, SkeletalNF-E2-Related Factor 2Organelle BiogenesisOxidation-ReductionOxidative StressAdenosine TriphosphatasesGlutathioneIsothiocyanatesLuciferasesNfe2l2 protein, mouseNF-E2-Related Factor 2sulforaphaneSulfoxidesThiobarbituric Acid Reactive Substances

Identifiers

PMID29018242
PMCPMC5635018
OpenAlexW2763973158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.