Evidence map›Paper›PMID 29018122›Full record

ArticlemBio2017

The BvgAS Regulon of

Kyung Moon, Richard P Bonocora, David D Kim, Qing Chen, Joseph T Wade, Scott Stibitz, Deborah M Hinton

Open access · goldAbstract read
In one paragraph

Article in mBio, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 72 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Proteomic comparison of epidemic AustralianMicrobiology spectrum · 2025
    Article
  6. Review
  7. The virulence regulatorJournal of bacteriology · 2025
    Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. mBio · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Avirulent phenotype promotesEmerging microbes & infections · 2023
    Article
  17. Article
  18. Pathogens and global health · 2023
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Kyung MoonGene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA kyung.moon@nih.gov dhinton@helix.nih.gov.
Richard P BonocoraWadsworth Center, New York State Department of Health, Albany, New York, USA.
David D KimGene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Qing ChenDivision of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
Joseph T WadeWadsworth Center, New York State Department of Health, Albany, New York, USA.
Scott StibitzDivision of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, Maryland, USA.
Deborah M HintonGene Expression and Regulation Section, Laboratory of Cell and Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA kyung.moon@nih.gov dhinton@helix.nih.gov.
Center for Biologics Evaluation and Research · USNational Institute of Diabetes and Digestive and Kidney Diseases · USNational Institutes of Health · USNew York State Department of Health · USUniversity at Albany, State University of New York · US

Funding

Genomics Core FacilityZICDK071001 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI HANOVER, JOHN A. · 2009 to 2023
$16.6M
Pervasive transcription in bacterial genomesDP2OD007188 · OD · WADSWORTH CENTER · PI WADE, JOSEPH THOMAS · 2010 to 2010
$2.4M
NIH HHS DP2 OD007188
6 · The paper itself

Abstract

Nearly all virulence factors in

Indexed as

RegulonBacterial ProteinsBordetella pertussisGene Expression Regulation, BacterialGenes, RegulatorHigh-Throughput Nucleotide SequencingPromoter Regions, GeneticReverse Transcriptase Polymerase Chain ReactionSignal TransductionTranscription FactorsTranscriptomeVirulenceBacterial ProteinsBvgA protein, BacteriabvgS protein, Bordetella pertussisTranscription FactorsbrpLBvgAS regulonpertussisRNA polymeraseRNA-seq

Identifiers

PMID29018122
PMCPMC5635692
OpenAlexW2761656312

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.