ReviewEnvironmental health perspectives2017
Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge.
Review in Environmental health perspectives, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 129 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
129 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Meta-analysis on short-term exposure to ambient ultrafine particles and respiratory morbidity.European respiratory review : an official journal of the European Respiratory Society · 2020Pooled it
- Exposure to Environmental and Occupational Particulate Air Pollution as a Potential Contributor to Neurodegeneration and Diabetes: A Systematic Review of Epidemiological Research.International journal of environmental research and public health · 2018Pooled it
- First-in-human controlled inhalation of thin graphene oxide nanosheets to study acute cardiorespiratory responses.Nature nanotechnology · 2024Trial
- Ultrafine Airborne Particle Deposition and Clearance in an Avian Lung under Ecologically Relevant Conditions.Environmental science & technology · 2026Article
- Effects of Fine Particulate Matter on Systemic Inflammatory Biomarkers in Elderly Patients with Chronic Obstructive Pulmonary Disease Versus the Healthy Elderly: A Pilot Study.International journal of molecular sciences · 2026Article
- Experimentally recreated workplace environments contain submicron crystalline silica particles, including ultrafine particles, which have been identified in the mediastinal lymph nodes of construction workers.Occupational and environmental medicine · 2026Article
- Radon and Non-Cancer Pulmonary Health Effects in Children: A State of The Art Review.Pediatric pulmonology · 2026Review
- Environmental modulators of vascular physiology and inflammation.Experimental physiology · 2026Review
- Insights into the causal role of diesel exhaust particles in ventricular arrhythmogenesis: protective effects of antioxidant cerium oxide nanoparticles.Particle and fibre toxicology · 2025Article
- Fiber length and shape-dependent differences in hepatic nanomaterial localization in mice following pulmonary exposure.Particle and fibre toxicology · 2025Article
- Application of nanoparticles in the treatment of acute lung injury: Current situation and future directions.Materials today. Bio · 2025Review
- An Online Measurement Approach to Monitor the Deposition of Diesel Exhaust Particles on Lung Cells In Vitro.Environmental science & technology · 2025Article
- Air pollution and alveolar health.European respiratory review : an official journal of the European Respiratory Society · 2025Review
- Dynamic QSAR modeling for predicting in vivo genotoxicity and inflammation induced by nanoparticles and advanced materials: a time-dose-property/response approach.Journal of nanobiotechnology · 2025Article
- Do We Know Enough About the Safety Profile of Silver Nanoparticles in Oncology? A Focus on Novel Methods and Approaches.International journal of molecular sciences · 2025Review
- Application of Smart Packaging on the Preservation of Different Types of Perishable Fruits.Foods (Basel, Switzerland) · 2025Review
- Combustion-derived carbon nanoparticles cause delayed apoptosis in neutrophil-like HL-60 cells in vitro and in primed human neutrophilic granulocytes ex vivo.Particle and fibre toxicology · 2025Article
- Occupational exposure to ultrafine particles and lung cancer in a population exposed to asbestos.BMC public health · 2025Article
- Examining the bacterial diversity including extracellular vesicles in air and soil: implications for human health.PloS one · 2025Article
- Airborne Nanoparticle Concentrations Are Associated with Increased Mortality Risk in Canada's Two Largest Cities.American journal of respiratory and critical care medicine · 2024Article
69 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
19 authors.
Funding
Abstract
backgroundA rich body of literature exists that has demonstrated adverse human health effects following exposure to ambient air particulate matter (PM), and there is strong support for an important role of ultrafine (nanosized) particles. At present, relatively few human health or epidemiology data exist for engineered nanomaterials (NMs) despite clear parallels in their physicochemical properties and biological actions in
objectivesNMs are available with a range of physicochemical characteristics, which allows a more systematic toxicological analysis. Therefore, the study of ultrafine particles (UFP, <100 nm in diameter) provides an opportunity to identify plausible health effects for NMs, and the study of NMs provides an opportunity to facilitate the understanding of the mechanism of toxicity of UFP.
methodsA workshop of experts systematically analyzed the available information and identified 19 key lessons that can facilitate knowledge exchange between these discipline areas. DISCUSSION: Key lessons range from the availability of specific techniques and standard protocols for physicochemical characterization and toxicology assessment to understanding and defining dose and the molecular mechanisms of toxicity. This review identifies a number of key areas in which additional research prioritization would facilitate both research fields simultaneously.
conclusionThere is now an opportunity to apply knowledge from NM toxicology and use it to better inform PM health risk research and vice versa. https://doi.org/10.1289/EHP424.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.