Evidence map›Paper›PMID 29017175›Full record

ArticleStereotactic and functional neurosurgery2017

Body Weight Changes after Deep Brain Stimulation for Obsessive-Compulsive Disorder or Depression.

Rosalie S N Linssen, Marloes S Oudijn, Mariska Mantione, Pepijn van den Munckhof, Damiaan Denys, P Richard Schuurman

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Stereotactic and functional neurosurgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Rosalie S N LinssenDepartment of Psychiatry, Academic Medical Center, Amsterdam, The Netherlands.
Marloes S Oudijn
Mariska Mantione
Pepijn van den Munckhof
Damiaan Denys
P Richard Schuurman
Amsterdam UMC Location University of Amsterdam · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn 2010, we published an often-cited case report describing smoking cessation and substantial weight loss after deep brain stimulation (DBS) for obsessive-compulsive disorder (OCD) in an obese patient. To test whether this single observation was also observed in the treated population at large, the weight changes of a larger cohort of patients who underwent DBS for OCD or major depressive disorder (MDD) were studied.

resultsData were available for 46 patients (30 OCD and 16 MDD patients; mean age 46.2 years, SD 10.9) with an average baseline body mass index (BMI) of 28.0 (SD 7.3), 26 of whom (57%) were overweight (n = 11), obese (n = 12), or morbidly obese (n = 3). Mean follow-up was 3.8 years (range 10 months to 8.7 years, SD 2.3), after which the average BMI was 28.1 (SD 7.0), not significantly different from baseline. The average BMI of the 15 patients with (morbid) obesity at baseline decreased from 36.8 to 34.6 (ns), while the average BMI of the 31 normal or "only" overweight patients at baseline increased from 23.8 to 25.0 (ns).

conclusionThere was no significant change in body weight on group level after DBS for either OCD or MDD.

Indexed as

Body Mass IndexAdultBody WeightDeep Brain StimulationFemaleFollow-Up StudiesHumansMajor Depressive DisorderMaleMiddle AgedObsessive-Compulsive DisorderWeight LossBody mass indexDeep brain stimulationDepressionObesityObsessive-compulsive disorderWeight

Identifiers

PMID29017175
PMCPMC5804846
OpenAlexW2761786755

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.