Evidence map›Paper›PMID 29016793›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2018

Mining 100 million notes to find homelessness and adverse childhood experiences: 2 case studies of rare and severe social determinants of health in electronic health records.

Cosmin A Bejan, John Angiolillo, Douglas Conway, Robertson Nash, Jana K Shirey-Rice, Loren Lipworth, Robert M Cronin, Jill Pulley, Sunil Kripalani, Shari Barkin and 2 more

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
75citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

75 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
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  10. SDoH-GPT: using large language models to extract social determinants of health.Journal of the American Medical Informatics Association : JAMIA · 2026
    Article
  11. Using reasoning LLMs to extract SDOH events from clinical notes.Proceedings. IEEE International Conference on Healthcare Informatics · 2026
    Article
  12. Article
  13. Article
  14. Article
  15. Synth-SBDH: A Synthetic Dataset of Social and Behavioral Determinants of Health for Clinical Text.Proceedings of the Conference on Empirical Methods in Natural Language Processing. Conference on Empirical Methods in Natural Language Processing · 2025
    Article
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  17. Review
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15 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Cosmin A BejanDepartment of Biomedical Informatics.
John AngiolilloDepartment of Medicine.
Douglas ConwayInstitute for Clinical and Translational Research.
Robertson NashDepartment of Medicine.
Jana K Shirey-RiceInstitute for Clinical and Translational Research.
Loren LipworthDepartment of Medicine.
Robert M CroninDepartment of Biomedical Informatics.
Jill PulleyDepartment of Medicine.
Sunil KripalaniDepartment of Medicine.
Shari BarkinDepartment of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Kevin B JohnsonDepartment of Biomedical Informatics.
Joshua C DennyDepartment of Biomedical Informatics.

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
From GWAS to PheWAS: Scanning the EMR Phenome for Gene-disease AssociationsR01LM010685 · NLM · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BASTARACHE, LISA · 2011 to 2022
$6.3M
Informatics Tools for Pharmacogenomic Discovery using Practice-based DataR01GM103859 · NIGMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DENNY, JOSHUA C., PATHAK, JYOTISHMAN · 2014 to 2017
$2.4M
NCATS NIH HHS UL1 TR000445NIGMS NIH HHS R01 GM103859NLM NIH HHS R01 LM010685
6 · The paper itself

Abstract

Objective: Understanding how to identify the social determinants of health from electronic health records (EHRs) could provide important insights to understand health or disease outcomes. We developed a methodology to capture 2 rare and severe social determinants of health, homelessness and adverse childhood experiences (ACEs), from a large EHR repository. Materials and Methods: We first constructed lexicons to capture homelessness and ACE phenotypic profiles. We employed word2vec and lexical associations to mine homelessness-related words. Next, using relevance feedback, we refined the 2 profiles with iterative searches over 100 million notes from the Vanderbilt EHR. Seven assessors manually reviewed the top-ranked results of 2544 patient visits relevant for homelessness and 1000 patients relevant for ACE. Results: word2vec yielded better performance (area under the precision-recall curve [AUPRC] of 0.94) than lexical associations (AUPRC = 0.83) for extracting homelessness-related words. A comparative study of searches for the 2 phenotypes revealed a higher performance achieved for homelessness (AUPRC = 0.95) than ACE (AUPRC = 0.79). A temporal analysis of the homeless population showed that the majority experienced chronic homelessness. Most ACE patients suffered sexual (70%) and/or physical (50.6%) abuse, with the top-ranked abuser keywords being "father" (21.8%) and "mother" (15.4%). Top prevalent associated conditions for homeless patients were lack of housing (62.8%) and tobacco use disorder (61.5%), while for ACE patients it was mental disorders (36.6%-47.6%). Conclusion: We provide an efficient solution for mining homelessness and ACE information from EHRs, which can facilitate large clinical and genetic studies of these social determinants of health.

Indexed as

Adverse Childhood ExperiencesElectronic Health RecordsIll-Housed PersonsSocial Determinants of HealthChildComputational BiologyData MiningHumansadverse childhood experiencesEHRhomelessnesssocial determinants of healthtext mining

Identifiers

PMID29016793
PMCPMC6080810

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.