Evidence map›Paper›PMID 29016669›Full record

ArticlePloS one2017

Major depressive disorder and suicide risk among adult outpatients at several general hospitals in a Chinese Han population.

Haiyan Li, Xinni Luo, Xiaoyin Ke, Qing Dai, Wei Zheng, Chanjuan Zhang, Ryan M Cassidy, Jair C Soares, XiangYang Zhang, Yuping Ning

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 3 pooled it
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 90 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Haiyan LiSouthern Medical University, Guangzhou, China.
Xinni LuoGuangzhou Medical University Affiliated Brain Hospital, Guangzhou Huiai Hospital, Guangzhou, China.
Xiaoyin KeGuangzhou Medical University Affiliated Brain Hospital, Guangzhou Huiai Hospital, Guangzhou, China.
Qing DaiGuangzhou Medical University Affiliated Brain Hospital, Guangzhou Huiai Hospital, Guangzhou, China.
Wei ZhengGuangzhou Medical University Affiliated Brain Hospital, Guangzhou Huiai Hospital, Guangzhou, China.
Chanjuan ZhangGuangzhou Medical University Affiliated Brain Hospital, Guangzhou Huiai Hospital, Guangzhou, China.
Ryan M CassidyDepartment of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
Jair C SoaresDepartment of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
XiangYang ZhangDepartment of Psychiatry and Behavioral Sciences, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America.
Yuping NingSouthern Medical University, Guangzhou, China.ORCID http://orcid.org/0000-0002-5727-2782
Guangzhou Psychiatric Hospital · CNThe University of Texas Health Science Center at Houston · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSomatic complaints are often the presenting symptoms of major depressive disorder (MDD) in the outpatient context, because this may go unrecognized. It is well understood that MDD carries an increased risk of suicide. This study aimed to identify the risk factors and association with both MDD and suicidality among Han Chinese outpatients.

methodsA multicenter study was carried out in 5189 outpatient adults (≥18 years old) in four general hospitals in Guangzhou, China. The 1392 patients who had the Patient Health Questionnaire-9 (PHQ-9) score ≥ 5, indicating depressive symptoms were offered an interview with a psychiatrist by the Mini International Neuropsychiatric Interview (MINI); 819 patients consented and completed the MINI interview. MINI module B was used to assess suicidality. Stepwise binary logistic models were used to estimate the relationship between a significant risk factor and suicide or MDD. According to with or without MDD, the secondary analysis was performed using the logistic regression model for the risk of suicidility.

resultsThe current prevalence of MDD and the one month prevalence of suicidality were 3.7% and 2.3% respectively. The odds ratio of suicidality in women was more than twice that in men (OR = 2.62; 95% CI 1.45-4.76). Other risk factors which were significantly associated with suicidality were: living alone, higher education, self-reported depression, getting psychiatric diagnoses (MDD, anxiety disorders, and bipolar disorders). Significant risk factors for MDD were also noticed, such as comorbid anxiety disorders, self-reported anxiety, insomnia, suicidal ideation. LIMITATION: It's a cross-sectional study in outpatient clinics using self-report questionnaires.

conclusionThis study provides valuable data about the risk factors and association of MDD and suicide risk in adult outpatients in Han Chinese. Those factors allow better the employment of preventative measures.

Indexed as

Hospitals, GeneralSuicidal IdeationAdultAnxietyChinaCross-Sectional StudiesDepressionFemaleHumansLogistic ModelsLonelinessMajor Depressive DisorderMaleMiddle AgedOdds RatioOutpatients

Identifiers

PMID29016669
PMCPMC5634639
OpenAlexW2762721869

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.