Evidence map›Paper›PMID 29016506›Full record

ArticleObstetrics and gynecology2017

Contraception and Conception After Bariatric Surgery.

Marie N Menke, Wendy C King, Gretchen E White, Gabriella G Gosman, Anita P Courcoulas, Gregory F Dakin, David R Flum, Molly J Orcutt, Alfons Pomp, Walter J Pories and 4 more

Registry-linked trialOpen access · bronzeAbstract readMulticenter Study
In one paragraph

Article in Obstetrics and gynecology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00465829 (Longitudinal Assessment of Bariatric Surgery), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00465829 completednot on this map

Longitudinal Assessment of Bariatric Surgery (LABS-2)

TypeobservationalSponsorUniversity of PittsburghRan2006 to 2016Enrolled2,458ConditionsObesity
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 43 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Article
  5. Review
  6. Article
  7. Pregnancy after bariatric surgery - a narrative literature review.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2021
    Review
  8. Article
  9. Article
  10. Review
  11. Pregnancy after bariatric surgery: Consensus recommendations for periconception, antenatal and postnatal care.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2019
    Review
  12. Healthcare provider knowledge regarding oral contraception effectiveness for women with a history of bariatric malabsorptive procedures.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019
    Article
  13. Sexual behaviors, risks, and sexual health outcomes for adolescent females following bariatric surgery.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019
    Article
  14. Conception rates and contraceptive use after bariatric surgery among women with infertility: Evidence from a prospective multicenter cohort study.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2019
    Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Marie N MenkeUniversity of Pittsburgh School of Medicine, the University of Pittsburgh Graduate School of Public Health, and the University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; Weill Cornell University Medical Center, New York, New York; the University of Washington, Seattle, Washington; the Neuropsychiatric Research Institute, Fargo, North Dakota; Brody School of Medicine, East Carolina University, Greenville, North Carolina; Oregon Health & Science University, Portland, Oregon; North Dakota State University, Fargo, North Dakota; and the National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland.
Wendy C King
Gretchen E White
Gabriella G Gosman
Anita P Courcoulas
Gregory F Dakin
David R Flum
Molly J Orcutt
Alfons Pomp
Walter J Pories
Jonathan Q Purnell
Kristine J Steffen
Bruce M Wolfe
Susan Z Yanovski
Cornell University · US

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
UNIVERSITY OF PITTSBURGH CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTE: BPCAUL1RR024153 · NCRR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2006 to 2011
$73.9M
CTSA INFRASTRUCTURE FOR PEDIATRIC RESEARCHUL1RR024996 · NCRR · WEILL MEDICAL COLL OF CORNELL UNIV · PI IMPERATO-MCGINLEY, JULIANNE L · 2007 to 2011
$49.6M
ZIPRASIDONE IN NORMAL HEPATIC FUNCTION SUBJECTS &IN HEPATIC DYSFUCTIN SUBJECTSM01RR000037 · NCRR · UNIVERSITY OF WASHINGTON · PI PIHOKER, CATHERINE · 1985 to 2007
$33.8M
Continuation of the Longitudinal Assessment of Bariatric Surgery (LABS) - DCCU01DK066557 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BELLE, STEVEN H. · 2003 to 2015
$15.8M
BARIATRIC SURGERY CLINICAL RESEARCH CONSORTIUMU01DK066555 · NIDDK · UNIVERSITY OF CALIFORNIA DAVIS · PI WOLFE, BRUCE M · 2003 to 2013
$6.2M
Effect of Bariatric Surgery on Insulin Resistance &CVDU01DK066585 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COURCOULAS, ANITA P · 2003 to 2013
$5.0M
Bariatric Surgery: Outcomes & Impact on PathophysiologyU01DK066667 · NIDDK · MOUNT SINAI SCHOOL OF MEDICINE OF NYU · PI BERK, PAUL DAVID, POMP, ALFONS · 2003 to 2015
$4.7M
Longtitudinal Assessment of Bariatric Surgery (LABS)U01DK066568 · NIDDK · UNIVERSITY OF WASHINGTON · PI FLUM, DAVID R · 2003 to 2013
$4.3M
East Carolina University Bariatric Surgery Clinical CenterU01DK066526 · NIDDK · EAST CAROLINA UNIVERSITY · PI PORIES, WALTER JULIUS · 2003 to 2015
$4.0M
Magee-Womens Basic and Translational Reproductive Health Training ProgramK12HD063087 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI EDWARDS, ROBERT PAGE · 2009 to 2019
$3.7M
Longitudinal Assessment of Bariatric Surgery (LABS)U01DK066471 · NIDDK · SANFORD RESEARCH NORTH · PI MITCHELL, JAMES EDWARD · 2003 to 2015
$3.7M
NCATS NIH HHS UL1 TR002384NCRR NIH HHS M01 RR000037NCRR NIH HHS UL1 RR024153NCRR NIH HHS UL1 RR024996NICHD NIH HHS K12 HD063087NIDDK NIH HHS U01 DK066471NIDDK NIH HHS U01 DK066526NIDDK NIH HHS U01 DK066555NIDDK NIH HHS U01 DK066557NIDDK NIH HHS U01 DK066568NIDDK NIH HHS U01 DK066585NIDDK NIH HHS U01 DK066667
6 · The paper itself

Abstract

objectiveTo examine contraceptive practices and conception rates after bariatric surgery.

methodsThe Longitudinal Assessment of Bariatric Surgery-2 is a multicenter, prospective cohort study of adults undergoing first-time bariatric surgery as part of routine clinical care at 10 U.S. hospitals. Recruitment occurred between 2005 and 2009. Participants completed preoperative and annual postsurgical assessments for up to 7 years until January 2015. This report was restricted to women 18-44 years old with no history of menopause, hysterectomy, or estrogen and progesterone therapy. Primary outcomes were self-reported contraceptive practices, overall conception rate, and early (less than 18 months) postsurgical conception. Contraceptive practice (no intercourse, protected intercourse, unprotected intercourse, or tried to conceive) was classified based on the preceding year. Conception rates were determined from self-reported pregnancies.

resultsOf 740 eligible women, 710 (95.9%) completed follow-up assessment(s). Median (interquartile range) preoperative age was 34 (30-39) years. In the first postsurgical year, 12.7% (95% CI 9.4-16.0) of women had no intercourse, 40.5% (95% CI 35.6-45.4) had protected intercourse only, 41.5% (95% CI 36.4-46.6) had unprotected intercourse while not trying to conceive, and 4.3% (95% CI 2.4-6.3) tried to conceive. The prevalence of the first three groups did not significantly differ across the 7 years of follow-up (P for all >.05); however, more women tried to conceive in the second year (13.1%, 95% CI 9.3-17.0; P<.001). The conception rate was 53.8 (95% CI 40.0-71.1) per 1,000 woman-years across follow-up (median [interquartile range] 6.5 [5.9-7.0] years); 42.3 (95% CI 30.2-57.6) per 1,000 woman-years in the 18 months after surgery. Age (adjusted relative risk 0.41 [95% CI 0.19-0.89] per 10 years, P=.03), being married or living as married (adjusted relative risk 4.76 [95% CI 2.02-11.21], P<.001), and rating future pregnancy as important preoperatively (adjusted relative risk 8.50 [95% CI 2.92-24.75], P<.001) were associated with early conception.

conclusionsPostsurgical contraceptive use and conception rates do not reflect recommendations for an 18-month delay in conception after bariatric surgery. CLINICAL

trial registrationClinicalTrials.gov, NCT00465829.

Indexed as

FertilizationAdolescentAdultBariatric SurgeryContraceptionContraception BehaviorFemaleFollow-Up StudiesHumansLongitudinal StudiesObesityPostoperative PeriodPregnancyPregnancy RateProspective StudiesYoung Adult

Identifiers

PMID29016506
PMCPMC5679259
OpenAlexW2763169980

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.