ArticleThe American journal of tropical medicine and hygiene2017
Demographic, Socioeconomic, and Geographic Factors Leading to Severe Malaria and Delayed Care Seeking in Ugandan Children: A Case-Control Study.
Article in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Delay in malaria care-seeking for children under five in Africa: a systematic review.Malaria journal · 2026Pooled it
- Pooled it
- Pooled it
- Understanding the context of delays in seeking appropriate care for children with symptoms of severe malaria in Uganda.PloS one · 2019Trial
- Assessing the impact of climate and control interventions on spatio-temporal malaria dynamics using a stochastic metapopulation model.PLoS computational biology · 2026Article
- Using sentinel surveillance system data to characterize severe malaria illness and quality of malaria case management among hospitalized patients in Kenya, 2017-2024.Malaria journal · 2026Article
- Article
- Predictors and characteristics of malaria treatment-seeking in Malawi: a longitudinal cohort study.Malaria journal · 2025Article
- The 24, 2 hours initiative: a game changer in malaria mortality reduction.Malaria journal · 2025Review
- Malaria prevalence and its determinants across 19 sub-Saharan African countries: a spatial and geographically weighted regression analysis.Malaria journal · 2025Article
- Non-falciparum malaria infections in Uganda, does it matter? A review of the published literature.Malaria journal · 2024Review
- Malaria in under-five children: prevalence and multi-factor analysis of high-risk African countries.BMC public health · 2024Article
- Factors influencing delay in malaria treatment seeking at selected public health facilities in South Gonder, Ethiopia.Scientific reports · 2024Article
- Comparing field-collected versus remotely-sensed variables to model malaria risk in the highlands of western Uganda.Malaria journal · 2023Article
- Severe malaria in Gabon: epidemiological, clinical and laboratory features in Amissa Bongo Hospital of Franceville.Malaria journal · 2023Article
- Health itinerary-related survival of children under-five with severe malaria or bloodstream infection, DR Congo.PLoS neglected tropical diseases · 2023Article
- Factors Associated with Severe Malaria among Patients under Reference to District Hospitals: A Cross-Sectional Study in Rusizi District, Rwanda.Rwanda journal of medicine and health sciences · 2023Article
- Malaria treatment health seeking behaviors among international students at the University of Ghana Legon.PloS one · 2023Article
- Spatial distribution of suspected and confirmed cholera cases in Mwanza City, Northern Tanzania.PLOS global public health · 2023Article
- The spectrum of clinical biomarkers in severe malaria and new avenues for exploration.Virulence · 2022Review
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
We studied associations between delayed care seeking, demographic, socioeconomic, and geographic factors and likelihood of severe malaria in Ugandan children. The study was based at Jinja Hospital, Uganda. We enrolled 325 severe malaria cases and 325 uncomplicated malaria controls matched by age and residence. Patient details, an itinerary of events in response to illness, household information, and location of participants' residences were captured. Conditional logistic regression was used to determine risk factors for severe malaria and delayed care seeking. Delayed care seeking (≥ 24 hours after fever onset; odds ratio [OR] 5.50; 95% confidence interval [CI] 2.70, 11.1), seeking care at a drug shop as the initial response to illness (OR 3.62; 95% CI 1.86, 7.03), and increasing distance from place of residence to the nearest health center (OR 1.45; 95% CI 1.17, 1.79) were independent risk factors for severe malaria. On subgroup analysis, delayed care seeking was a significant risk factor in children with severe malaria attributable to severe anemia (OR 15.6; 95% CI 3.02, 80.6), but not unconsciousness (OR 1.13; 95% CI 0.30, 4.28). Seeking care at a drug shop (OR 2.84; 95% CI 1.12, 7.21) and increasing distance to the nearest health center (OR 1.18; 95% CI 1.01, 1.37) were independent risk factors for delayed care seeking. Delayed care seeking and seeking care at a drug shop were risk factors for severe malaria. Seeking care at a drug shop was also a predictor of delayed care seeking. The role of drug shops in contributing to delayed care and risk of severe malaria requires further study.
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