Evidence map›Paper›PMID 29016302›Full record

ArticleThe American journal of tropical medicine and hygiene2017

Diagnosis of Louse-Borne Relapsing Fever despite Negative Microscopy in Two Asylum Seekers from Eastern Africa.

Spinello Antinori, Cristina Tonello, Sophie Edouard, Carlo Parravicini, Daniela Gastaldi, Romualdo Grande, Laura Milazzo, Davide Ricaboni, Florence Fenollar, Didier Raoult and 2 more

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Prevalence of Lyme Disease and Relapsing FeverPathogens (Basel, Switzerland) · 2024
    Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Spinello AntinoriIII Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Milano, Italy.
Cristina TonelloPathology Unit, Ospedale L. Sacco, ASST Fatebenefratelli Sacco, Milano, Italy.
Sophie EdouardUnité de Recherche sur le Maladies Infectieuses et Tropicales Émergentes (URMITIE) IRD198, CNRS 7278, INSERM 1095, Institute Hospitalo-Universitarie (IHU) Méditerranée-Infection, Aix-Marseille Université, Faculté de Médecine, Marseille, France.
Carlo ParraviciniPathology Unit, Ospedale L. Sacco, ASST Fatebenefratelli Sacco, Milano, Italy.
Daniela GastaldiCentro Accoglienza Immigrati, Milano, Italy.
Romualdo GrandeClinical Microbiology, Virology and Bioemergence Diagnostics, Ospedale L Sacco, ASST Fatebenefratelli Sacco, Milano, Italy.
Laura MilazzoIII Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Milano, Italy.
Davide RicaboniUnité de Recherche sur le Maladies Infectieuses et Tropicales Émergentes (URMITIE) IRD198, CNRS 7278, INSERM 1095, Institute Hospitalo-Universitarie (IHU) Méditerranée-Infection, Aix-Marseille Université, Faculté de Médecine, Marseille, France.
Florence FenollarUnité de Recherche sur le Maladies Infectieuses et Tropicales Émergentes (URMITIE) IRD198, CNRS 7278, INSERM 1095, Institute Hospitalo-Universitarie (IHU) Méditerranée-Infection, Aix-Marseille Université, Faculté de Médecine, Marseille, France.
Didier RaoultUnité de Recherche sur le Maladies Infectieuses et Tropicales Émergentes (URMITIE) IRD198, CNRS 7278, INSERM 1095, Institute Hospitalo-Universitarie (IHU) Méditerranée-Infection, Aix-Marseille Université, Faculté de Médecine, Marseille, France.
Mario CorbellinoIII Division of Infectious Diseases, ASST Fatebenefratelli Sacco, Milano, Italy.
Oleg MediannikovUnité de Recherche sur le Maladies Infectieuses et Tropicales Émergentes (URMITIE) IRD198, CNRS 7278, INSERM 1095, Institute Hospitalo-Universitarie (IHU) Méditerranée-Infection, Aix-Marseille Université, Faculté de Médecine, Marseille, France.
ASST Fatebenefratelli Sacco · ITUnité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes · FRCentre National de la Recherche Scientifique · FRInserm · FRUniversity of Milan · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report two cases of louse-borne relapsing fever observed at our Institution in June 2016. Both patients were young asylum seekers from Africa who had recently arrived in Milan, Italy. Notably, direct microscopic examination of peripheral blood smears was repeatedly negative for the presence of spirochetes and the diagnosis, supported by clinical and epidemiologic evidence, required molecular confirmation by polymerase chain reaction amplification of DNA extracted from blood and sequencing of the amplified products.

Indexed as

AdultAnti-Bacterial AgentsBorreliaDNA, BacterialDoxycyclineHumansItalyMaleMicroscopyPolymerase Chain ReactionRefugeesRelapsing FeverSomaliaSudanAnti-Bacterial AgentsDNA, BacterialDoxycycline

Identifiers

PMID29016302
PMCPMC5805056
OpenAlexW2759884177

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.