Evidence map›Paper›PMID 28994740›Full record

ArticleMolecules (Basel, Switzerland)2017

Antibacterial and Antitubercular Activities of Cinnamylideneacetophenones.

Carlos R Polaquini, Guilherme S Torrezan, Vanessa R Santos, Ana C Nazaré, Débora L Campos, Laíza A Almeida, Isabel C Silva, Henrique Ferreira, Fernando R Pavan, Cristiane Duque and 1 more

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Antimicrobial Activity of Cinnamaldehyde onFrontiers in microbiology · 2019
    Article
  5. Design of Antibacterial Agents: Alkyl Dihydroxybenzoates againstInternational journal of molecular sciences · 2018
    Article
  6. Antimycobacterial Activity of Cinnamaldehyde in aMolecules (Basel, Switzerland) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Carlos R PolaquiniLaboratory of Green and Medicinal Chemistry, Department of Chemistry and Environmental Sciences, Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University (Unesp), São José do Rio Preto, SP 15054-000, Brazil. carlos_polaquini@hotmail.com.ORCID 0000-0001-5913-0246
Guilherme S TorrezanLaboratory of Green and Medicinal Chemistry, Department of Chemistry and Environmental Sciences, Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University (Unesp), São José do Rio Preto, SP 15054-000, Brazil. guilherme_panz@hotmail.com.
Vanessa R SantosDepartment of Pediatric Dentistry and Public Health, School of Dentistry, São Paulo State University (Unesp), Araçatuba, SP 16015-050, Brazil. vanessarodrigues_22@hotmail.com.
Ana C NazaréLaboratory of Green and Medicinal Chemistry, Department of Chemistry and Environmental Sciences, Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University (Unesp), São José do Rio Preto, SP 15054-000, Brazil. carolnazare@uol.com.br.
Débora L CamposDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (Unesp), Araraquara, SP 14800-903, Brazil. leite.debora26@gmail.com.
Laíza A AlmeidaLaboratory of Green and Medicinal Chemistry, Department of Chemistry and Environmental Sciences, Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University (Unesp), São José do Rio Preto, SP 15054-000, Brazil. laiza_araujo1@hotmail.com.ORCID 0000-0002-9907-6309
Isabel C SilvaDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (Unesp), Araraquara, SP 14800-903, Brazil. isabelcrs10@gmail.com.ORCID 0000-0001-9617-9858
Henrique FerreiraDepartment of Biochemistry and Microbiology, Institute of Biosciences, São Paulo State University (Unesp), Rio Claro, SP 13506-900, Brazil. henfer@rc.unesp.br.ORCID 0000-0002-9183-9420
Fernando R PavanDepartment of Biological Sciences, School of Pharmaceutical Sciences, São Paulo State University (Unesp), Araraquara, SP 14800-903, Brazil. fernandopavan@fcfar.unesp.br.ORCID 0000-0002-6969-3963
Cristiane DuqueDepartment of Pediatric Dentistry and Public Health, School of Dentistry, São Paulo State University (Unesp), Araçatuba, SP 16015-050, Brazil. cristianeduque@yahoo.com.br.ORCID 0000-0002-2575-279X
Luis O RegasiniLaboratory of Green and Medicinal Chemistry, Department of Chemistry and Environmental Sciences, Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University (Unesp), São José do Rio Preto, SP 15054-000, Brazil. regasini@ibilce.unesp.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cinnamaldehyde is a natural product with broad spectrum of antibacterial activity. In this work, it was used as a template for design and synthesis of a series of 17 cinnamylideneacetophenones. Phenolic compounds

Indexed as

AcetophenonesAnti-Bacterial AgentsAntitubercular AgentsCell LineComputer SimulationHumansLungMicrobial Sensitivity TestsMolecular StructureMycobacterium tuberculosisStaphylococcus aureusStreptococcus mutansStreptococcus sanguisStructure-Activity RelationshipAcetophenonesAnti-Bacterial AgentsAntitubercular AgentsantibacterialantimicrobialantitubercularcinnamaldehydecinnamylideneacetophenoneClaisen-Schmidt reactionMycobacterium

Identifiers

PMID28994740
PMCPMC6151560

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.