Evidence map›Paper›PMID 28994406›Full record

ArticleActa crystallographica. Section F, Structural biology communications2017

Crystallization via tubing microfluidics permits both in situ and ex situ X-ray diffraction.

Charline J J Gerard, Gilles Ferry, Laurent M Vuillard, Jean A Boutin, Leonard M G Chavas, Tiphaine Huet, Nathalie Ferte, Romain Grossier, Nadine Candoni, Stéphane Veesler

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta crystallographica. Section F, Structural biology communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Microfluidic Devices for High-Throughput In Situ Serial Crystallography.Advances in biochemical engineering/biotechnology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Charline J J GerardCINaM-CNRS, Aix-Marseille Université, Campus de Luminy, Case 913, 13288 Marseille CEDEX 09, France.
Gilles FerryInstitut de Recherches Servier, 125 Chemin de Ronde, 78290 Croissy-sur-Seine, France.
Laurent M VuillardInstitut de Recherches Servier, 125 Chemin de Ronde, 78290 Croissy-sur-Seine, France.
Jean A BoutinInstitut de Recherches Servier, 125 Chemin de Ronde, 78290 Croissy-sur-Seine, France.
Leonard M G ChavasPROXIMA-1, Synchrotron SOLEIL, Gif-sur-Yvette, France.
Tiphaine HuetPROXIMA-1, Synchrotron SOLEIL, Gif-sur-Yvette, France.
Nathalie FerteCINaM-CNRS, Aix-Marseille Université, Campus de Luminy, Case 913, 13288 Marseille CEDEX 09, France.
Romain GrossierCINaM-CNRS, Aix-Marseille Université, Campus de Luminy, Case 913, 13288 Marseille CEDEX 09, France.
Nadine CandoniCINaM-CNRS, Aix-Marseille Université, Campus de Luminy, Case 913, 13288 Marseille CEDEX 09, France.
Stéphane VeeslerCINaM-CNRS, Aix-Marseille Université, Campus de Luminy, Case 913, 13288 Marseille CEDEX 09, France.

Funding

Horizon 2020 708130
6 · The paper itself

Abstract

A microfluidic platform was used to address the problems of obtaining diffraction-quality crystals and crystal handling during transfer to the X-ray diffractometer. Crystallization conditions of a protein of pharmaceutical interest were optimized and X-ray data were collected both in situ and ex situ.

Indexed as

CrystallizationMicrofluidicsX-Ray Diffractioncrystallizationex situ X-ray diffractionin situ X-ray diffractionmicrofluidicsoptimization

Identifiers

PMID28994406
PMCPMC5633925

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.