ArticleeLife2017
Molecular architecture underlying fluid absorption by the developing inner ear.
Open access · goldAbstract read
In one paragraph
Article in eLife, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 58 citations in OpenAlex.
- A single-nucleus transcriptomic atlas of human inner ear development.Nature neuroscience · 2026Article
- Research progress on the mechanisms and animal models of Ménière's disease.Genes & diseases · 2026Review
- Postnatal Slc26a4 gene therapy improves hearing and structural integrity in a hereditary hearing loss model.The Journal of clinical investigation · 2026Article
- Hyperplastic growth, not hydrostatic distension, in endolymphatic hydrops in humans challenges the classic view of Meniere's disease.Scientific reports · 2025Article
- Bilateral Enlarged Vestibular Aqueduct: Auditory, Genetic and Radiological Characterization, and Benefits of Cochlear Implants.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025Article
- A single-cell transcriptomic atlas of inner ear morphogenesis in zebrafish.bioRxiv : the preprint server for biology · 2025Article
- Inhibitors of the ubiquitin‑proteasome system rescue cellular levels and ion transport function of pathogenic pendrin (SLC26A4) protein variants.International journal of molecular medicine · 2025Article
- Paired and solitary ionocytes in the zebrafish olfactory epithelium.Chemical senses · 2025Article
- Comparative genomic profiling of SLC26A4-expressing cells in the inner ear and other organs.PloS one · 2025Article
- Common genetic etiologies of sensorineural hearing loss in Koreans.Genomics & informatics · 2024Review
- Comparison of GWAS results between de novo tinnitus and cancer treatment-related tinnitus suggests distinctive roles for genetic risk factors.Scientific reports · 2024Article
- Environmental and molecular control of tissue-specific ionocyte differentiation in zebrafish.Development (Cambridge, England) · 2024Article
- SLC26A4-AP-2 mu2 interaction regulates SLC26A4 plasma membrane abundance in the endolymphatic sac.Science advances · 2024Article
- Advance and Application of Single-cell Transcriptomics in Auditory Research.Neuroscience bulletin · 2024Review
- Environmental and molecular control of tissue-specific ionocyte differentiation in zebrafish.bioRxiv : the preprint server for biology · 2024Article
- SLC26 Anion Transporters.Handbook of experimental pharmacology · 2024Review
- CHD7 variants associated with hearing loss and enlargement of the vestibular aqueduct.Human genetics · 2023Article
- Acquired CFTR dysfunction and dense distribution of ionocytes in nasal mucosa of children with CRS.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023Article
- A single-cell level comparison of human inner ear organoids with the human cochlea and vestibular organs.Cell reports · 2023Article
- Defining developmental trajectories of prosensory cells in human inner ear organoids at single-cell resolution.Development (Cambridge, England) · 2023Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Keiji HondaMolecular Biology and Genetics Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, United States.ORCID 0000-0002-3411-8539
Sung Huhn KimAnatomy and Physiology Department, Kansas State University, Manhattan, United States.
Michael C KellyDevelopmental Neuroscience Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, United States.
Joseph C BurnsDevelopmental Neuroscience Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, United States.
Laura ConstanceAnatomy and Physiology Department, Kansas State University, Manhattan, United States.
Xiangming LiAnatomy and Physiology Department, Kansas State University, Manhattan, United States.
Fei ZhouAnatomy and Physiology Department, Kansas State University, Manhattan, United States.
Michael HoaAuditory Development and Restoration Program, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, United States.ORCID 0000-0001-7469-2909
Matthew W KelleyDevelopmental Neuroscience Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, United States.
Philine WangemannAnatomy and Physiology Department, Kansas State University, Manhattan, United States.
Robert J MorellGenomics and Computational Biology Core, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, United States.
Andrew J GriffithMolecular Biology and Genetics Section, National Institute on Deafness and Other Communication Disorders, National Institutes of Health, Bethesda, United States.
National Institutes of Health · USKansas State University · US
Funding
Hair Cell Development in the Mammalian CochleaZIADC000059 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI KELLEY, MATTHEW · 2009 to 2025
$41.8MTRANSEPITHELIAL ION TRANSPORT &ITS REGULATIONP20RR017686 · NCRR · KANSAS STATE UNIVERSITY · PI MELGAREJO GARCIA, LUIS TONATIUH · 2002 to 2011
$21.8MGenomic and Computational Biology Support for NIDCD Intramural ResearchZICDC000086 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI MORELL, ROBERT J · 2015 to 2025
$19.8MMolecular Analysis Of Human Hereditary DeafnessZIADC000060 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI ROUX, ISABELLE · 2009 to 2022
$18.4MCellular and Molecular Pathways for Hearing Restoration in the Adult Inner EarZIADC000088 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI HOA, MICHAEL · 2015 to 2025
$14.0MINTEGRATIVE MECHANISMS OF CORTICAL NEURONSR01DC000086 · NIDCD · YALE UNIVERSITY · PI SHEPHERD, GORDON · 1989 to 2010
$3.6MMolecular Analysis Of Human Hereditary DeafnessZ01DC000060 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI GRIFFITH, ANDREW J · 2001 to 2008
$3.0MHair Cell Development in the Mammalian CochleaZ01DC000059 · NIDCD · NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS · PI KELLEY, MATTHEW W · 2000 to 2008
$1.9MFluid transport in inner ear developmentR01DC012151 · NIDCD · KANSAS STATE UNIVERSITY · PI WANGEMANN, A. PHILINE · 2012 to 2016
$1.9MIntramural NIH HHS Z01 DC000059Intramural NIH HHS Z01 DC000060NCRR NIH HHS P20 RR017686NIDCD NIH HHS R01 DC000086NIDCD NIH HHS R01 DC012151
Abstract
Mutations of
Indexed as
AnimalsAnion Transport ProteinsEndolymphEndolymphatic SacGene Expression ProfilingMiceSodium ChlorideSulfate TransportersAnion Transport ProteinsSlc26a4 protein, mouseSodium ChlorideSulfate Transportersdevelopmental biologyendolymphatic sacgene arraymouseneuroscienceorgan cultureRNA-seqSlc26a4stem cells
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What OpenQuestion holds
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.