Evidence map›Paper›PMID 28994003›Full record

ArticleNeurochemical research2018

Muscarinic Acetylcholine Receptors Potentiate 5'-Adenosine Monophosphate-Activated Protein Kinase Stimulation and Glucose Uptake Triggered by Thapsigargin-Induced Store-Operated Ca

Maria C Olianas, Simona Dedoni, Pierluigi Onali

Abstract read
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In one paragraph

Article in Neurochemical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Role of STIM1 in the Regulation of Cardiac Energy Substrate Preference.International journal of molecular sciences · 2023
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Maria C OlianasLaboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, 09042, Monserrato, CA, Italy.
Simona DedoniLaboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, 09042, Monserrato, CA, Italy.
Pierluigi OnaliLaboratory of Cellular and Molecular Pharmacology, Section of Neurosciences, Department of Biomedical Sciences, University of Cagliari, Cittadella Universitaria di Monserrato, 09042, Monserrato, CA, Italy. onali@unica.it.ORCID http://orcid.org/0000-0002-9733-460X
University of Cagliari · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The 5'-adenosine monophosphate-activated protein kinase (AMPK) is a key regulator of the cellular energy metabolism and may induce either cell survival or death. We previously reported that in SH-SY5Y human neuroblastoma cells stimulation of muscarinic acetylcholine receptors (mAChRs) activate AMPK by triggering store-operated Ca

Indexed as

AMP-Activated Protein KinasesBiological TransportCalciumCalcium ChannelsCell LineGlucoseHumansNeoplasm ProteinsReceptors, MuscarinicSignal TransductionStromal Interaction Molecule 1ThapsigarginAMP-Activated Protein KinasesCalciumCalcium ChannelsGlucoseNeoplasm ProteinsReceptors, MuscarinicSTIM1 protein, humanStromal Interaction Molecule 1Thapsigargin5′-Adenosine monophosphate-activated protein kinaseGlucose uptakeHuman neuroblastoma cellsMuscarinic acetylcholine receptorsStore-operated Ca2+ entryThapsigargin

Identifiers

PMID28994003
OpenAlexW2761179465

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.