SynthesisClinical reviews in allergy & immunology2017
Skin Manifestations Associated with Autoimmune Liver Diseases: a Systematic Review.
Synthesis in Clinical reviews in allergy & immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.
- Extrarenal Immune-Mediated Disorders Linked with Acute Poststreptococcal Glomerulonephritis: a Systematic Review.Clinical reviews in allergy & immunology · 2019Pooled it
- [Cutaneous presentation of digestive tract disorders and liver disease].Dermatologie (Heidelberg, Germany) · 2026Review
- Frequency and Clinical Predictors of Cutaneous Manifestations in Patients With Chronic Liver Disease.Cureus · 2026Article
- Altered hepatic metabolism in Down syndrome.Cell reports · 2026Article
- Autoimmune Hepatitis Associated with Other Autoimmune Diseases: A Critical Review.Journal of clinical and translational hepatology · 2025Review
- Extracellular vesicle-mediated bidirectional communication between the liver and other organs: mechanistic exploration and prospects for clinical applications.Journal of nanobiotechnology · 2025Review
- Article
- Rosacea and autoimmune liver diseases: a two-sample Mendelian randomization study.Archives of dermatological research · 2024Article
- Alopecia in Patients with Autoimmune Hepatitis Treated by Tacrolimus Therapy.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024Article
- From Phenotype to Molecules: Unveiling the Genetic and Immunological Bridges Between Autoimmune Diseases and Vitiligo.Clinical, cosmetic and investigational dermatology · 2024Article
- Association of vitiligo with multiple cutaneous and extra-cutaneous autoimmune diseases: a nationwide cross-sectional study.Archives of dermatological research · 2023Article
- Primary biliary cirrhosis and psoriasis: a two-sample Mendelian randomization study.Frontiers in immunology · 2023Article
- [Cutaneous hyperpigmentation as a manifestation in acute on chronic liver failure].Revista medica del Instituto Mexicano del Seguro Social · 2022Article
- Autoimmune Hepatitis Associated With Cryoglobulinemic Vasculitis.ACG case reports journal · 2022Article
- Development of secretome-based strategies to improve cell culture protocols in tissue engineering.Scientific reports · 2022Article
- Autoimmmune hepatitis.Cellular & molecular immunology · 2022Review
- Association between celiac disease and vitiligo: A review of the literature.World journal of clinical cases · 2021Review
- Organ-organ communication: The liver's perspective.Theranostics · 2021Review
- Pyodermatitis-pyostomatitis vegetans associated with autoimmune hepatitis: unreported co-existence.Gastroenterology and hepatology from bed to bench · 2020Article
- Autoimmunity in 2017.Clinical reviews in allergy & immunology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Autoimmune liver diseases, which include mainly autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, and the variant syndromes, are often associated with extrahepatic autoimmune diseases. However, the association with cutaneous diseases is less well described. In the present article, we provide a systematic literature review on skin manifestations linked to each of these four autoimmune liver diseases, excluding skin manifestations of systemic diseases. The association of autoimmune hepatitis with vitiligo is well known, with a particular striking association with type 2 autoimmune hepatitis, a condition occurring almost entirely in children and adolescents, much rarer and more aggressive than type 1 autoimmune hepatitis; probable associations are also identified with alopecia areata, psoriasis, and pyoderma gangrenosum. Primary biliary cholangitis is not linked to lichen planus as previously assumed, but to vitiligo, psoriasis and the very rare amicrobial pustulosis of the folds. The proposed diagnostic criteria for this latter condition include the presence of anti-mitochondrial autoantibodies, the serological hallmark of primary biliary cholangitis. The very strong association of primary sclerosing cholangitis with inflammatory bowel diseases hampers the search for an association with skin diseases, since inflammatory bowel diseases have a strong association with various dermatological condition, including neutrophilic dermatoses and erythema nodosum. Nevertheless, a probable association of primary sclerosing cholangitis with psoriasis is identified in this review. Variant syndromes, also called overlap syndromes, are likely associated with vitiligo as well, which is not surprising, since autoimmune hepatitis is a feature of these conditions and they may share regions of the MHC.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.