ArticleFunctional & integrative genomics2018
Dynamic transcriptomic analysis in hircine longissimus dorsi muscle from fetal to neonatal development stages.
Article in Functional & integrative genomics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Comparative Analysis of the Transcriptome of the Chicken Breast Muscle at Different Developmental Stages.Animals : an open access journal from MDPI · 2026Article
- Identification of SNPs in the second intron ofAnimal biotechnology · 2025Article
- Exploring the landscape of circular RNAs in the development of skeletal muscle in Huaxi cattle.BMC genomics · 2025Article
- High Muscle Expression of IGF2BP1 Gene Promotes Proliferation and Differentiation of Chicken Primary Myoblasts: Results of Transcriptome Analysis.Animals : an open access journal from MDPI · 2024Article
- Transcriptome analysis revealed differences in gene expression in sheep muscle tissue at different developmental stages.BMC genomic data · 2024Article
- Dynamic Changes in the Global Transcriptome of Postnatal Skeletal Muscle in Different Sheep.Genes · 2023Article
- Integrative analysis of circRNA, miRNA, and mRNA profiles to reveal ceRNA regulation in chicken muscle development from the embryonic to post-hatching periods.BMC genomics · 2022Article
- Deep Small RNA Sequencing Reveals Important miRNAs Related to Muscle Development and Intramuscular Fat Deposition inFrontiers in veterinary science · 2022Article
- Screening of Genes Related to Growth, Development and Meat Quality of Sahan Crossbred F1 Sheep Based on RNA-Seq Technology.Frontiers in veterinary science · 2022Article
- Genome-Wide Selection Signatures and Human-Mediated Introgression Events inFrontiers in genetics · 2022Article
- Dynamic transcriptome profiles of postnatal porcine skeletal muscle growth and development.BMC genomic data · 2021Article
- Analysis of long intergenic non-coding RNAs transcriptomic profiling in skeletal muscle growth during porcine embryonic development.Scientific reports · 2021Article
- Transcriptome Analysis Reveals the Profile of Long Non-coding RNAs During Chicken Muscle Development.Frontiers in physiology · 2021Article
- Systematic analyses reveal RNA editing events involved in skeletal muscle development of goat (Capra hircus).Functional & integrative genomics · 2020Article
- Comparative Transcriptome Profile Analysis ofFrontiers in genetics · 2020Article
- Article
- Dynamic Transcriptomic Analysis of Breast Muscle Development From the Embryonic to Post-hatching Periods in Chickens.Frontiers in genetics · 2019Article
- Comparative transcriptomic analysis of skeletal muscle tissue during prenatal stages in Tongcheng and Yorkshire pig using RNA-seq.Functional & integrative genomics · 2018Article
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
Abstract
Muscle growth and development from fetal to neonatal stages consist of a series of delicately regulated and orchestrated changes in expression of genes. In this study, we performed whole transcriptome profiling based on RNA-Seq of caprine longissimus dorsi muscle tissue obtained from prenatal stages (days 45, 60, and 105 of gestation) and neonatal stage (the 3-day-old newborn) to identify genes that are differentially expressed and investigate their temporal expression profiles. A total of 3276 differentially expressed genes (DEGs) were identified (Q value < 0.01). Time-series expression profile clustering analysis indicated that DEGs were significantly clustered into eight clusters which can be divided into two classes (Q value < 0.05), class I profiles with downregulated patterns and class II profiles with upregulated patterns. Based on cluster analysis, GO enrichment analysis found that 75, 25, and 8 terms to be significantly enriched in biological process (BP), cellular component (CC), and molecular function (MF) categories in class I profiles, while 35, 21, and 8 terms to be significantly enriched in BP, CC, and MF in class II profiles. KEGG pathway analysis revealed that DEGs from class I profiles were significantly enriched in 22 pathways and the most enriched pathway was Rap1 signaling pathway. DEGs from class II profiles were significantly enriched in 17 pathways and the mainly enriched pathway was AMPK signaling pathway. Finally, six selected DEGs from our sequencing results were confirmed by qPCR. Our study provides a comprehensive understanding of the molecular mechanisms during goat skeletal muscle development from fetal to neonatal stages and valuable information for future studies of muscle development in goats.
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