Evidence map›Paper›PMID 28993891›Full record

ArticleDer Orthopade2018

Value of antibiotic prophylaxis in routine knee arthroscopy : A retrospective study.

Yongjian Qi, Xu Yang, Zhengqi Pan, Hua Wang, Liaobin Chen

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Article in Der Orthopade, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yongjian QiDepartment of Orthopaedic Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, 430071, Wuhan, Wuchang District, China.
Xu YangDepartment of Orthopaedic Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, 430071, Wuhan, Wuchang District, China.
Zhengqi PanDepartment of Orthopaedic Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, 430071, Wuhan, Wuchang District, China.
Hua WangDepartment of Orthopaedic Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, 430071, Wuhan, Wuchang District, China.
Liaobin ChenDepartment of Orthopaedic Surgery, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, 430071, Wuhan, Wuchang District, China. lbchen@whu.edu.cn.
Zhongnan Hospital of Wuhan University · CNWuhan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveProphylactic antibiotic use prior to routine knee arthroscopy remains controversial. It is important to know whether antibiotics help decrease the surgical site infection (SSI) rate. Our aims were to assess the efficacy of antibiotic prophylaxis in preventing SSI and to identify risk factors for SSI following routine knee arthroscopy without an implant.

methodsA retrospective study was conducted using the electronic medical records at the authors' hospital to identify patients that underwent routine knee arthroscopy without an implant between October 2010 and October 2016. Data on demographics, clinical characteristics and antibiotic administration were extracted. Arthroscopic diagnosis, debridement, partial or complete meniscectomy, arthroscopic shaving and microfracture, removal of loose bodies, synovectomy and lateral retinacular release were included. Complex knee arthroscopy with an implant was excluded. Patients were divided into evaluation (with prophylactic antibiotics) and control (no antibiotic treatment) groups. Continuous variables between groups were compared using the Student's t-test. Data were analyzed using the Chi-squared test for percentages between groups. Multivariate logistic regression was used to identify independent risk factors of SSI.

resultsOf 1326 patients, 614 (46.3%) received prophylactic antibiotics, while 712 (53.7%) did not. There were seven (0.53%) SSIs. The SSI rate did not differ significantly between patients receiving antibiotics (0.49%, three) and those not (0.56%, four). Five patients (0.37%) had superficial infections, two (0.33%) were in the prophylactic antibiotic group and three (0.42%) were in the other group. Deep infections occurred in two patients (0.15%), one (0.16%) in the prophylactic antibiotic group and one (0.14%) in the other group. The difference between the two groups was not statistically significant (P = 1.0). Age over 50 years was associated with an increased risk of SSI (relative ratio [RR] = 1.469, 95% confidence interval [CI] 1.09-2.13, P = 0.009).

conclusionsProphylactic antibiotic use in routine knee arthroscopy without an implant may not be necessary. Age over 50 years was associated with an increased risk of SSI.

Indexed as

AdultAge FactorsAntibiotic ProphylaxisArthroscopyCross InfectionFemaleHumansKneeMaleMiddle AgedRetrospective StudiesRisk FactorsSurgical Wound InfectionTreatment OutcomeImplantMethicillin-resistant Staphylococcus aureusProphylactic antibioticsRoutine knee arthroscopySurgical site infection

Identifiers

PMID28993891
OpenAlexW2761659360

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.