ArticleExperimental brain research2017
Resting GABA concentration predicts inhibitory control during an auditory Go-Nogo task.
Article in Experimental brain research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 20 citations in OpenAlex.
- Relationships between GABA + and Glx concentrations with age and inhibition in healthy older adults.Brain structure & function · 2025Article
- GABAergic polygenic risk for cocaine use disorder is negatively correlated with precuneus activity during cognitive control in African American individuals.Addictive behaviors · 2021Article
- Effect of Age in Auditory Go/No-Go Tasks: A Magnetoencephalographic Study.Brain sciences · 2020Article
- Suggestions for improving the visualization of magnetic resonance spectroscopy voxels and spectra.Royal Society open science · 2020Article
- Dysfunction of Inferior Parietal Lobule During Sensory Gating in Patients With Amnestic Mild Cognitive Impairment.Frontiers in aging neuroscience · 2020Article
- Automatic inhibitory function in the human somatosensory and motor cortices: An MEG-MRS study.Scientific reports · 2017Article
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Authors and funding
5 authors at 4 institutions in 1 country.
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Abstract
Inhibitory control plays an important role in goal-directed behavior. Although substantial inter-individual variability exists in the behavioral performance of response inhibition, the corresponding modulating neurochemical and neurophysiological mechanisms remain unclear. Thus, the present study aimed to explore the relationship between behavioral response inhibition, GABA+ concentrations and automatic sensory gating (SG) in the auditory cortices. We recruited 19 healthy adults to undergo magnetoencephalography, magnetic resonance spectroscopy (MRS), and behavioral experiments. A paired-stimulus paradigm was used to study SG of the auditory cortices, and an auditory-driven Go-Nogo task was used to evaluate the behavioral response inhibition. Resting GABA+ concentrations were measured in the bilateral superior temporal gyri by means of MRS. Neither GABA+ concentrations nor auditory SG showed significant hemispheric asymmetry. However, an enhanced SG (lower ratio) was found to correlate with improved behavioral inhibition. Moreover, a higher GABA+ concentration was strongly related to improved inhibitory control. These findings highlight the important role of automatic neurophysiological processes and inhibitory neurotransmitters in the prediction of the behavioral performance of inhibitory control.
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