Evidence map›Paper›PMID 28993856›Full record

ReviewDer Pathologe2017

[Malignant lymphomas of the eye].

F Fend, D Süsskind, C Deuter, S E Coupland

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Pathologe, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. [Retinal manifestation in hematological diseases].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

F FendInstitut für Pathologie und Neuropathologie, Comprehensive Cancer Center Tübingen-Stuttgart, Universitätsklinikum Tübingen, Eberhard Karls Universität Tübingen, Liebermeisterstraße 8, 72076, Tübingen, Deutschland. falko.fend@med.uni-tuebingen.de.
D SüsskindDepartment für Augenheilkunde, Universitätsklinikum Tübingen, Eberhard Karls Universität Tübingen, Tübingen, Deutschland.
C DeuterDepartment für Augenheilkunde, Universitätsklinikum Tübingen, Eberhard Karls Universität Tübingen, Tübingen, Deutschland.
S E CouplandDepartment of Cellular and Molecular Pathology, University of Liverpool, Liverpool, Großbritannien.
University of Tübingen · DEUniversitätsklinikum Tübingen · DEUniversity of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The eye and the ocular adnexae are rare sites for malignant non-Hodgkin lymphoma (NHL). Based on their anatomical location, intraocular lymphomas must be discerned from NHL of adnexal structures including conjunctiva, lacrimal gland, and orbit. Whereas the latter group mostly consists of indolent extranodal marginal zone B‑cell lymphomas of mucosa-associated lymphoid tissue (MALT) type or secondary manifestations of systemic NHL, most primary intraocular lymphomas are classified as diffuse large B‑cell lymphomas (DLBCL) and are considered a variant of primary DLBCL of the central nervous system. The most common form is primary vitreoretinal lymphoma (PVRL), which presents with nonspecific symptoms and is difficult to discern from uveitis. Diagnosis of PVRL is usually made by cytological, immunocytochemical, and molecular analysis of vitreous aspirates. Degenerative changes, limited material, and the occurrence of pseudoclonality in the molecular analysis of B‑cell clonality can hamper diagnostic assessment. Novel techniques such as detection of MYD88 mutations common in PVRL can increase diagnostic sensitivity. Close cooperation with clinical colleagues and rapid specimen processing are fundamental for successful diagnosis.

Indexed as

Eye NeoplasmsHumansLymphoma, B-Cell, Marginal ZoneLymphoma, Large B-Cell, DiffuseB-cell lymphomaLymphoma, vitreoretinalMarginal zone lymphomaMasquerade syndromeNon-Hodgkin lymphoma

Identifiers

PMID28993856
OpenAlexW2764304774

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.