Evidence map›Paper›PMID 28993843›Full record

ArticleHerz2018

In-hospital mortality after acute STEMI in patients undergoing primary PCI.

M Ali, S A Lange, T Wittlinger, G Lehnert, A G Rigopoulos, M Noutsias

Abstract read
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In one paragraph

Article in Herz, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Culprit vessel-related myocardial mechanics and prognostic implications following acute myocardial infarction.Clinical research in cardiology : official journal of the German Cardiac Society · 2020
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  6. Observational
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M AliDepartment of Cardiology, heart catheterization laboratory, Asklepios Harzklinik Goslar, Kösliner Straße 12, 38642, Goslar, Germany. dr-mali@hotmail.de.
S A LangeDepartment of Cardiology, heart catheterization laboratory, Asklepios Harzklinik Goslar, Kösliner Straße 12, 38642, Goslar, Germany.
T WittlingerDepartment of Cardiology, heart catheterization laboratory, Asklepios Harzklinik Goslar, Kösliner Straße 12, 38642, Goslar, Germany.
G LehnertDepartment of Cardiology, heart catheterization laboratory, Asklepios Harzklinik Goslar, Kösliner Straße 12, 38642, Goslar, Germany.
A G RigopoulosMid-German Heart Center, Department of Internal Medicine III, Division of Cardiology, Angiology and Intensive Medical Care, University Hospital Halle, Martin Luther University Halle, Ernst-Grube-Straße 40, 06120, Halle (Saale), Germany.
M NoutsiasMid-German Heart Center, Department of Internal Medicine III, Division of Cardiology, Angiology and Intensive Medical Care, University Hospital Halle, Martin Luther University Halle, Ernst-Grube-Straße 40, 06120, Halle (Saale), Germany.ORCID http://orcid.org/0000-0002-9066-5262

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAcute myocardial infarction (AMI) is the main cause of global and in-hospital mortality in patients with cardiovascular diseases. We aimed to examine the association between the coronary artery involved and the in-hospital mortality in patients who underwent primary percutaneous coronary intervention (pPCI) after ST segment elevation myocardial infarction (STEMI).

methodsThe in-hospital mortality of STEMI patients who underwent pPCI was assessed at the Department of Cardiology, Harzklinik Goslar, Germany, which has no access to immediate mechanical circulatory support (MCS), between 2013 and 2017.

resultsWe enrolled 312 STEMI patients, with a mean age of 67.1 ± 13.4 years, of whom 211 (68%) were male. In-hospital mortality was documented in 31 patients (10%). In-hospital mortality was associated with pre-hospital cardiopulmonary resuscitation (CPR; n = 39/12.5%), older age, lower systolic blood pressure, Killip class > 1, triple-vessel disease (each p < 0.0001), female gender (p = 0.0158), and with the localization of the treated culprit lesion in the left main coronary artery (LMCA; p = 0.0083) and in the ramus circumflexus (RCX; p = 0.0141).

conclusionIn this monocentric cohort, all-cause in-hospital mortality of STEMI patients after pPCI was significantly higher in those patients with culprit lesions in the LMCA and in the RCX, which may prove to be a substantial novel risk factor for STEMI-related mortality. Increasing age and female gender may be interdependent risk factors for mortality in this patient population. Furthermore, our data highlight the importance of the availability of MCS options in pPCI centers for patients after CPR.

Indexed as

Hospital MortalityPercutaneous Coronary InterventionST Elevation Myocardial InfarctionAgedAged, 80 and overFemaleGermanyHumansMaleMiddle AgedProspective StudiesRetrospective StudiesRisk FactorsTreatment OutcomeCulprit lesionHospital mortalityPercutaneous coronary interventionPrognosisST segment elevation myocardial infarction

Identifiers

PMID28993843

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.