Evidence map›Paper›PMID 28993729›Full record

ArticleFrontiers in pharmacology2017

Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses.

Bjorn Baselet, Omid Azimzadeh, Nadine Erbeldinger, Mayur V Bakshi, Till Dettmering, Ann Janssen, Svetlana Ktitareva, Donna J Lowe, Arlette Michaux, Roel Quintens and 8 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Biological effects of high-LET irradiation on the circulatory system.International journal of radiation biology · 2025
    Pooled it
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  3. Effect of radiotherapy on the DNA cargo and cellular uptake mechanisms of extracellular vesicles.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 3 countries.

Bjorn BaseletRadiobiology Unit, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre (SCK•CEN)Mol, Belgium.
Omid AzimzadehInstitute of Radiation Biology, Helmholtz Zentrum Munich, German Research Center for Environmental HealthMunich, Germany.
Nadine ErbeldingerGSI Helmholtz Centre for Heavy Ion ResearchDarmstadt, Germany.
Mayur V BakshiInstitute of Radiation Biology, Helmholtz Zentrum Munich, German Research Center for Environmental HealthMunich, Germany.
Till DettmeringGSI Helmholtz Centre for Heavy Ion ResearchDarmstadt, Germany.
Ann JanssenRadiobiology Unit, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre (SCK•CEN)Mol, Belgium.
Svetlana KtitarevaGSI Helmholtz Centre for Heavy Ion ResearchDarmstadt, Germany.
Donna J LoweDepartment of Radiation Effects, Centre for Radiation, Chemical and Environmental Hazards, Public Health EnglandDidcot, United Kingdom.
Arlette MichauxRadiobiology Unit, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre (SCK•CEN)Mol, Belgium.
Roel QuintensRadiobiology Unit, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre (SCK•CEN)Mol, Belgium.
Kenneth RajDepartment of Radiation Effects, Centre for Radiation, Chemical and Environmental Hazards, Public Health EnglandDidcot, United Kingdom.
Marco DuranteGSI Helmholtz Centre for Heavy Ion ResearchDarmstadt, Germany.
Claudia FournierGSI Helmholtz Centre for Heavy Ion ResearchDarmstadt, Germany.
Mohammed A BenotmaneRadiobiology Unit, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre (SCK•CEN)Mol, Belgium.
Sarah BaatoutRadiobiology Unit, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre (SCK•CEN)Mol, Belgium.
Pierre SonveauxPole of Pharmacology and Therapeutics, Institut de Recherche Expérimentale et Clinique, Université catholique de LouvainBrussels, Belgium.
Soile TapioInstitute of Radiation Biology, Helmholtz Zentrum Munich, German Research Center for Environmental HealthMunich, Germany.
An AertsRadiobiology Unit, Institute for Environment, Health and Safety, Belgian Nuclear Research Centre (SCK•CEN)Mol, Belgium.
Belgian Nuclear Research Centre · BEGSI Helmholtz Centre for Heavy Ion Research · DEHelmholtz Zentrum München · DEPublic Health England · GBUCLouvain · BETechnical University of Darmstadt · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cardiovascular diseaseendothelial cellsFe ionsirradiationlinear energy transferradiotherapyX-rays

Identifiers

PMID28993729
PMCPMC5622284
OpenAlexW2759135485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.