Evidence map›Paper›PMID 28993671›Full record

ArticleScientific reports2017

MDSCs are induced after experimental blunt chest trauma and subsequently alter antigen-specific T cell responses.

Yvonne Hüsecken, Sylvia Muche, Monika Kustermann, Malena Klingspor, Annette Palmer, Sonja Braumüller, Markus Huber-Lang, Klaus-Michael Debatin, Gudrun Strauss

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
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  7. Club Cell Protein 16 Attenuates CD16Journal of immunology research · 2021
    Article
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  15. Article
  16. Innate immune responses to trauma.Nature immunology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Yvonne HüseckenDepartment of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Sylvia MucheDepartment of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Monika KustermannDepartment of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Malena KlingsporDepartment of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Annette PalmerInstitute of Clinical and Experimental Trauma Immunology, University Medical Center Ulm, Ulm, Germany.
Sonja BraumüllerInstitute of Clinical and Experimental Trauma Immunology, University Medical Center Ulm, Ulm, Germany.
Markus Huber-LangInstitute of Clinical and Experimental Trauma Immunology, University Medical Center Ulm, Ulm, Germany.
Klaus-Michael DebatinDepartment of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany.
Gudrun StraussDepartment of Pediatrics and Adolescent Medicine, University Medical Center Ulm, Ulm, Germany. gudrun.strauss@uniklinik-ulm.de.
University Hospital Ulm · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe blunt chest trauma (TxT) induces a strong inflammatory response with posttraumatic immune suppression pointing to an impaired adaptive immune response. Since CD11b

Indexed as

AnimalsCell ProliferationCytokinesDisease Models, AnimalEpitopesImmunosuppression TherapyInflammationLungLymphocyte CountMaleMice, Inbred C57BLMyeloid-Derived Suppressor CellsSpleenTh1 CellsThoracic InjuriesT-LymphocytesCytokinesEpitopes

Identifiers

PMID28993671
PMCPMC5634472
OpenAlexW2761584116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.