ArticleScientific reports2017
Contralateral cortico-ponto-cerebellar pathways reconstruction in humans in vivo: implications for reciprocal cerebro-cerebellar structural connectivity in motor and non-motor areas.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 138 papers, 7 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
138 citing papers in PubMed, 7 syntheses or guidelines pooled it, 232 citations in OpenAlex.
- Exploring Hemispheric Vulnerability in Crossed Cerebellar Diaschisis: A Systematic Review and Meta-Analysis.Behavioural neurology · 2026Pooled it
- A bias-accounting meta-analytic approach refines and expands the cerebellar behavioral topography.Neuroscience and biobehavioral reviews · 2025Pooled it
- Effects of Cerebellar Transcranial Magnetic Stimulation on the Motor Function of Patients With Stroke: A Systematic Review and Meta-Analysis.Brain and behavior · 2025Pooled it
- The Role of the Human Cerebellum for Learning from and Processing of External Feedback in Non-Motor Learning: A Systematic Review.Cerebellum (London, England) · 2024Pooled it
- Systematic Review and Meta-analysis of Language Symptoms due to Cerebellar Injury.Cerebellum (London, England) · 2023Pooled it
- Cerebral Cortical Activity Following Non-invasive Cerebellar Stimulation-a Systematic Review of Combined TMS and EEG Studies.Cerebellum (London, England) · 2020Pooled it
- The role of the cerebellum in adaptation: ALE meta-analyses on sensory feedback error.Human brain mapping · 2019Pooled it
- Exploring Neurobiological Effects of Intermittent Theta-Burst Stimulation on the Left Cerebellum for Post-stroke Unilateral Neglect: A Preliminary Transcranial Magnetic Stimulation-Electroencephalography Investigation.Cerebellum (London, England) · 2025Trial
- Cerebellar Asymmetry of Motivational Direction: Anger-Dependent Effects of Cerebellar Transcranial Direct Current Stimulation on Aggression in Healthy Volunteers.Cerebellum (London, England) · 2024Trial
- White matter predictors of cerebellar tDCS treatment effects in aphasia rehabilitation.Frontiers in neurologyTrial
- Functional development of midbrain and pons during human gestation and electrophysiological markers for DS intervention.Journal of advanced research · 2026Article
- EEG-ECeG Coherence Mapping of Human Cerebro-cerebellar Projections: An Exploratory Study.Cerebellum (London, England) · 2026Article
- Spatial analysis of paraneoplastic cerebellar degeneration in ovarian cancer with anti-Yo syndrome and SCA1.Journal of neurology · 2026Article
- Modeling framework disentangles cerebellar mechanisms in speech feedback control, revealing trade-offs reshaped by degeneration.bioRxiv : the preprint server for biology · 2026Article
- Cerebellar Tracts Microstructural Characteristics and Severity of Language Impairment in Post-stroke Patients with Aphasia: A DTI Study.Cerebellum (London, England) · 2026Article
- The cerebro-cerebellar system: Integrative roles in motor control, cognition, and neuropsychiatric disorders.IBRO neuroscience reports · 2026Review
- A Multi-Subject Tractography Atlas of Human Cerebellar Connections.Research square · 2026Article
- Diaschisis as Cerebello-Cortical Loop Dysfunction in Acute Ischemic Stroke: A Network Framework for Outcome Variability.Brain sciences · 2026Review
- Cerebellar growth is associated with domain-specific cerebral maturation and socio-linguistic behavior.Nature communications · 2026Article
- Anatomically constrained and curated cerebellar tractography (ACCURAT): an open framework and a pathway-specific neuroanatomical reference.bioRxiv : the preprint server for biology · 2026Article
78 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebellar involvement in cognition, as well as in sensorimotor control, is increasingly recognized and is thought to depend on connections with the cerebral cortex. Anatomical investigations in animals and post-mortem humans have established that cerebro-cerebellar connections are contralateral to each other and include the cerebello-thalamo-cortical (CTC) and cortico-ponto-cerebellar (CPC) pathways. CTC and CPC characterization in humans in vivo is still challenging. Here advanced tractography was combined with quantitative indices to compare CPC to CTC pathways in healthy subjects. Differently to previous studies, our findings reveal that cerebellar cognitive areas are reached by the largest proportion of the reconstructed CPC, supporting the hypothesis that a CTC-CPC loop provides a substrate for cerebro-cerebellar communication during cognitive processing. Amongst the cerebral areas identified using in vivo tractography, in addition to the cerebral motor cortex, major portions of CPC streamlines leave the prefrontal and temporal cortices. These findings are useful since provide MRI-based indications of possible subtending connectivity and, if confirmed, they are going to be a milestone for instructing computational models of brain function. These results, together with further multi-modal investigations, are warranted to provide important cues on how the cerebro-cerebellar loops operate and on how pathologies involving cerebro-cerebellar connectivity are generated.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.