Evidence map›Paper›PMID 28993463›Full record

ArticleJournal of cell science2017

Pib2 and the EGO complex are both required for activation of TORC1.

Natalia V Varlakhanova, Michael J Mihalevic, Kara A Bernstein, Marijn G J Ford

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cell science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 45 citations in OpenAlex.

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  15. Article
  16. Regulation of Amino Acid Transport in Saccharomyces cerevisiae.Microbiology and molecular biology reviews : MMBR · 2019
    Review
  17. Article
  18. Article
  19. Article
  20. Frontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Natalia V VarlakhanovaDepartment of Cell Biology and Physiology, University of Pittsburgh School of Medicine, 3500 Terrace Street, Pittsburgh, PA 15261, USA.
Michael J MihalevicDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, 5117 Centre Avenue, Pittsburgh, PA 15213, USA.
Kara A BernsteinDepartment of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, 5117 Centre Avenue, Pittsburgh, PA 15213, USA.
Marijn G J FordDepartment of Cell Biology and Physiology, University of Pittsburgh School of Medicine, 3500 Terrace Street, Pittsburgh, PA 15261, USA marijn@pitt.edu.ORCID http://orcid.org/0000-0002-9115-4413
University of Pittsburgh · US

Funding

Replication fork dynamics and repair by Rad51 paralogues after DNA alkylationR01ES024872 · NIEHS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BERNSTEIN, KARA A · 2015 to 2019
$2.4M
The Roles of the Dynamin-Related Protein Vps1 and the ESCRT Complex in MicroautophagyR01GM120102 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FORD, MARIJN GERARD JOHANNES · 2016 to 2020
$1.5M
NIEHS NIH HHS R01 ES024872NIGMS NIH HHS R01 GM120102
6 · The paper itself

Abstract

The TORC1 complex is a key regulator of cell growth and metabolism in

Indexed as

Apoptosis Regulatory ProteinsAutophagyEnzyme ActivationIntracellular MembranesPhosphatidylinositol 3-KinasesProtein TransportSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsSignal TransductionTranscription FactorsVacuolesApoptosis Regulatory ProteinsMEH1 protein, S cerevisiaePhosphatidylinositol 3-KinasesPib2 protein, S cerevisiaeSaccharomyces cerevisiae ProteinsTORC1 protein complex, S cerevisiaeTranscription FactorsEGO complexGtr1Gtr2Pib2TORC1

Identifiers

PMID28993463
PMCPMC5702048
OpenAlexW2761743895

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.