Evidence map›Paper›PMID 28993461›Full record

ArticleInfection and immunity2018

Brucella abortus Promotes a Fibrotic Phenotype in Hepatic Stellate Cells, with Concomitant Activation of the Autophagy Pathway.

Paula Constanza Arriola Benitez, Ayelén Ivana Pesce Viglietti, Claudia Karina Herrmann, Vida A Dennis, Diego José Comerci, Guillermo Hernán Giambartolomei, María Victoria Delpino

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.7field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. [Research progress on brucellosis combined with liver injury].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2025
    Review
  4. Review
  5. Analysis of Clinical Characteristics and Blood Cell in Adult Patients with Brucella Bloodstream Infection of Different Blood Groups.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2023
    Article
  6. Cell and Tissue Tropism of Brucella spp.Infection and immunity · 2023
    Review
  7. Uncovering the Hidden Credentials ofMicrobiology and molecular biology reviews : MMBR · 2021
    Review
  8. Review
  9. Article
  10. Bacteria Exploit Autophagy For Their Own Benefit.Infection and drug resistance · 2019
    Review
  11. Immunopathogenesis of Hepatic Brucellosis.Frontiers in cellular and infection microbiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Paula Constanza Arriola BenitezInstituto de Inmunología, Genética y Metabolismo (INIGEM), CONICET, Universidad de Buenos Aires, Buenos Aires, Argentina.
Ayelén Ivana Pesce VigliettiInstituto de Inmunología, Genética y Metabolismo (INIGEM), CONICET, Universidad de Buenos Aires, Buenos Aires, Argentina.
Claudia Karina HerrmannInstituto de Investigaciones Biotecnológicas, Dr. Rodolfo A. Ugalde (IIB-INTECH), CONICET, Universidad Nacional de San Martín, Buenos Aires, Argentina.
Vida A DennisCenter for NanoBiotechnology Research, Alabama State University, Montgomery, Alabama, USA.
Diego José ComerciInstituto de Investigaciones Biotecnológicas, Dr. Rodolfo A. Ugalde (IIB-INTECH), CONICET, Universidad Nacional de San Martín, Buenos Aires, Argentina.
Guillermo Hernán GiambartolomeiInstituto de Inmunología, Genética y Metabolismo (INIGEM), CONICET, Universidad de Buenos Aires, Buenos Aires, Argentina.
María Victoria DelpinoInstituto de Inmunología, Genética y Metabolismo (INIGEM), CONICET, Universidad de Buenos Aires, Buenos Aires, Argentina mdelpino@ffyb.uba.ar.
University of Buenos Aires · ARAlabama State University · USConsejo Nacional de Investigaciones Científicas y Técnicas · ARInstituto Tecnológico de Chascomús · ARNational University of General San Martín · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The liver is frequently affected in patients with active brucellosis. The present study demonstrates that

Indexed as

ApoptosisAutophagyBeclin-1Brucella abortusBrucellosisCaspase 3Cell LineCollagenFibrosisHepatic Stellate CellsHumansLiverLiver CirrhosisMatrix Metalloproteinase 9PhenotypeSignal TransductionBeclin-1Caspase 3CollagenMatrix Metalloproteinase 9Transforming Growth Factor beta1Type IV Secretion SystemsBrucellaliver

Identifiers

PMID28993461
PMCPMC5736806
OpenAlexW2763887644

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.