Observational studyBMJ open2017
Recurrent wheeze and its relationship with lung function and airway inflammation in preschool children: a cross-sectional study in South Korea.
Observational study in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- Bacterial composition and colony structure of the lower respiratory tract in infants and children with recurrent wheezing: a case-control study.Italian journal of pediatrics · 2022Article
- Does fetal leptin and adiponectin influence children's lung function and risk of wheeze?Journal of developmental origins of health and disease · 2021Article
- Asthma predictive index as a useful diagnostic tool in preschool children: a cross-sectional study in Korea.Clinical and experimental pediatrics · 2020Article
- Evolution of Airway Inflammation in Preschoolers with Asthma-Results of a Two-Year Longitudinal Study.Journal of clinical medicine · 2020Article
- Nitric Oxide and Biological Mediators in Pediatric Chronic Rhinosinusitis and Asthma.Journal of clinical medicine · 2019Review
- The risk of preschool asthma at 2-4 years is not associated with leukocyte telomere length at birth or at 1 year of age.Asia Pacific allergy · 2019Article
- Risk factors and prognosis of recurrent wheezing in Chinese young children: a prospective cohort study.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2019Article
- The Role of FeNO in Predicting Asthma.Frontiers in pediatrics · 2019Review
- Lung function tests to monitor respiratory disease in preschool children.Acta bio-medica : Atenei Parmensis · 2018Review
Corrections and comments
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Authors and funding
13 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRelationship between recurrent wheeze and airway function and inflammation in preschool children is not fully known.
objectiveTo investigate the relationship between recurrent wheeze and airway inflammation, lung function, airway hyper-reactivity (AHR) and atopy in preschool children.
designObservational study, comparing forced expiratory volume in 1 s (FEV
settingPopulation-based, cross-sectional study in Seoul and the Gyeonggi province of Korea conducted as a government-funded programme to perform standardised measurement of the prevalence of allergic diseases, and related factors, in preschool children.
participants900 children aged 4-6 years. PRIMARY AND SECONDARY OUTCOME MEASURES: eNO, FEV
methodsChildren completed the modified International Study of Asthma and Allergies in Childhood questionnaire and underwent eNO assessments, spirometry, methacholine bronchial provocation tests and skin prick tests. Recurrent wheeze was defined as having a lifetime wheeze of more than three episodes, based on the questionnaire. The frequency of hospitalisation and emergency room visits was also obtained by means of the questionnaire. 'Current' wheeze was defined as having symptoms or treatments within the past 12 months.
resultsThe prevalence of recurrent wheeze was 13.4%. Children with recurrent wheeze showed a higher prevalence of lifetime or current allergic rhinitis (p=0.01 and p=0.002, respectively) and lifetime atopic dermatitis (p=0.007). Children with recurrent wheeze showed lower FEV
conclusionsRecurrent wheeze in preschool children may be associated with airway inflammation and diminished airway function, but not with AHR or atopy.
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