Evidence map›Paper›PMID 28993388›Full record

Trial reportBMJ open2017

MEDication reminder APPs to improve medication adherence in Coronary Heart Disease (MedApp-CHD) Study: a randomised controlled trial protocol.

Karla Santo, Clara K Chow, Aravinda Thiagalingam, Kris Rogers, John Chalmers, Julie Redfern

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06034301 (Feasibility of Interventions Impacting Medication Adherence), which is not on this map. Cited by 31 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06034301 nacompletednot on this mapstarted 2023, after this paper: background citation

Feasibility of Interventions Impacting Medication Adherence

TypeinterventionalSponsorWashington University School of MedicineRan2023 to 2024Enrolled41ConditionsHypertension, Medication AdherenceArmsMedication Reminder App
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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  16. Information Needs and Communication Strategies for People with Coronary Heart Disease: A Scoping Review.International journal of environmental research and public health · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Karla SantoCardiovascular Division, The George Institute for Global Health, Sydney, Australia.ORCID http://orcid.org/0000-0001-9047-8865
Clara K ChowCardiovascular Division, The George Institute for Global Health, Sydney, Australia.
Aravinda ThiagalingamSydney Medical School, University of Sydney, Sydney, Australia.
Kris RogersStatistics Division, The George Institute for Global Health, Sydney, Australia.
John ChalmersSydney Medical School, University of Sydney, Sydney, Australia.
Julie RedfernCardiovascular Division, The George Institute for Global Health, Sydney, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe growing number of smartphone health applications available in the app stores makes these apps a promising tool to help reduce the global problem of non-adherence to long-term medications. However, to date, there is limited evidence that available medication reminder apps are effective. This study aims to determine the impact of medication reminder apps on adherence to cardiovascular medication when compared with usual care for people with coronary heart disease (CHD) and to determine whether an advanced app compared with a basic app is associated with higher adherence. METHODS AND ANALYSIS: Randomised controlled trial with follow-up at 3 months to evaluate the feasibility and effectiveness of medication reminder apps on medication adherence compared with usual care. An estimated sample size of 156 patients with CHD will be randomised to one of three groups (usual care group, basic medication reminder app group and advanced medication reminder app group). The usual care group will receive standard care for CHD with no access to a medication reminder app. The basic medication reminder app group will have access to a medication reminder app with a basic feature of providing simple daily reminders with no interactivity. The advanced medication reminder app group will have access to a medication reminder app with additional interactive and customisable features. The primary outcome is medication adherence measured by the eight-item Morisky Medication Adherence Scale at 3 months. Secondary outcomes include clinical measurements of blood pressure and cholesterol levels, and medication knowledge. A process evaluation will also be performed to assess the feasibility of the intervention by evaluating the acceptability, utility and engagement with the apps. ETHICS AND DISSEMINATION: Ethical approval has been obtained from the Western Sydney Local Health Network Human Research Ethics Committee (AU/RED/HREC/1/WMEAD/3). Study findings will be disseminated via usual scientific forums. TRIAL REGISTRATION NUMBER: ACTRN12616000661471; Pre-results.

Indexed as

Drug MonitoringMobile ApplicationsSmartphoneClinical ProtocolsCoronary DiseaseFeasibility StudiesHumansReminder SystemsSelf Reportapplicationsappscoronary heart diseaseeHealthMedication adherencemedication compliancemHealthmobile phonerandomised controlled trialsmartphone

Identifiers

PMID28993388
PMCPMC5640083

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.