Evidence map›Paper›PMID 28993364›Full record

ArticleBMJ case reports2017

Durable complete remission with combination chemotherapy and bortezomib in HIV-associated plasmablastic lymphoma.

Nivedita Arora, Arjun Gupta, Navid Sadeghi

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 83% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Plasmablastic Lymphoma. A State-of-the-Art Review: Part 2-Focus on Therapy.Mediterranean journal of hematology and infectious diseases · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nivedita AroraDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Arjun GuptaDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Navid SadeghiParkland Health and Hospital System, Dallas, Texas, USA.
The University of Texas Southwestern Medical Center · USParkland Health & Hospital System · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasmablastic lymphoma (PBL) is an aggressive form of non-Hodgkin's lymphoma (NHL) classically seen in patients infected with the human immunodeficiency virus, but can also be seen in other immunocompromised states such as transplant recipients, autoimmune diseases and the elderly. PBL is generally associated with a poor prognosis despite chemotherapy. There is evidence supporting the use of bortezomib in combination with standard chemotherapy to achieve durable responses in patients with PBL. We describe a patient with acquired immunodeficiency syndrome who presented with rectal pain and bright red blood per rectum. He was diagnosed with stage IVA PBL with anorectal, nodal, calvarial and hepatic involvement. Along with highly active antiretroviral therapy, he was treated with six cycles of dose adjusted etoposide, prednisone, vincristine, cyclophosphamide and doxorubicin (DA-EPOCH) plus bortezomib resulting in durable complete remission 30 months after diagnosis.

Indexed as

Acquired Immunodeficiency SyndromeAdultAntineoplastic AgentsAntineoplastic Combined Chemotherapy ProtocolsAnti-Retroviral AgentsBortezomibCyclophosphamideDoxorubicinEtoposideHumansInduction ChemotherapyMalePlasmablastic LymphomaPrednisoneVincristineAntineoplastic AgentsAnti-Retroviral AgentsBortezomibCyclophosphamideDoxorubicinEtoposidePrednisoneVincristinehiv / aidsmalignant and benign haematology

Identifiers

PMID28993364
PMCPMC5652596
OpenAlexW2763676546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.