Evidence map›Paper›PMID 28992464›Full record

ReviewCurrent opinion in immunology2017

Pathogenesis of infections in HIV-infected individuals: insights from primary immunodeficiencies.

Qian Zhang, Pierre Frange, Stéphane Blanche, Jean-Laurent Casanova

Abstract readReview
In one paragraph

Review in Current opinion in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 52 citations in OpenAlex.

  1. Article
  2. Review
  3. Expanding the scope of human immunology in theJournal of human immunity · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. The Microbe, the Infection Enigma, and the Host.Annual review of microbiology · 2024
    Review
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. From second thoughts on the germ theory to a full-blown host theory.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 3 countries.

Qian ZhangSidra Medical and Research Center, Doha, Qatar. Electronic address: qzhang@sidra.org.
Pierre FrangeDepartment of Clinical Microbiology, Hôpital Necker Enfants Malades, Assistance Publique - Hôpitaux de Paris (AP-HP), Paris, France; Pediatric Hematology and Immunology Unit, Hôpital Necker Enfants Malades, AP-HP, Paris, France.
Stéphane BlanchePediatric Hematology and Immunology Unit, Hôpital Necker Enfants Malades, AP-HP, Paris, France.
Jean-Laurent CasanovaPediatric Hematology and Immunology Unit, Hôpital Necker Enfants Malades, AP-HP, Paris, France; Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM, Hôpital Necker Enfants Malades, Paris, France; Paris Descartes University, Imagine Institute, Paris, France; St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, The Rockefeller University, New York, NY, USA; Howard Hughes Medical Institute, New York, NY, USA.
Hôpital Necker-Enfants Malades · FRSidra Medical and Research Center · QA

Funding

Howard Hughes Medical Institute
6 · The paper itself

Abstract

Following infection with almost any given microorganism other than an emerging pathogen, only a minority of individuals develop life-threatening clinical disease, implying that these individuals have some form of immunodeficiency. A growing number of inherited and acquired immunodeficiencies have been deciphered over the last 50 years. HIV infection is probably the best-known acquired immunodeficiency. It emerged about 40 years ago and precipitates various severe infections, the occurrence of which is associated with a fall in circulating CD4

Indexed as

AnimalsCandidiasisCD4-Positive T-LymphocytesHIV-1HIV InfectionsHumansImmunologic Deficiency SyndromesInfectionsSignal TransductionTh17 Cells

Identifiers

PMID28992464
PMCPMC5682227
OpenAlexW2763699513

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.