Evidence map›Paper›PMID 28992364›Full record

ArticleAcademic emergency medicine : official journal of the Society for Academic Emergency Medicine2018

Behavioral Changes in Children After Emergency Department Procedural Sedation.

Jean I Pearce, David C Brousseau, Ke Yan, Keri R Hainsworth, Raymond G Hoffmann, Amy L Drendel

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03980067 (Pediatric Procedural Sedation and the Relationship With Post-Discharge Negative Behavioral Changes in the Emergency Department), which is not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
0.8field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03980067 nacompletednot on this mapstarted 2019, after this paper: background citation

Pediatric Procedural Sedation and the Relationship With Post-Discharge Negative Behavioral Changes in the Emergency Department

TypeinterventionalSponsorMedical College of WisconsinRan2019 to 2022Enrolled201ConditionsBehavior, Child, AnxietyArmsVirtual Reality Game
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Incidence and predictors of nonresponse to intranasal midazolam in children undergoing laceration repair.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2025
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  6. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jean I PearceDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
David C BrousseauDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
Ke YanDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
Keri R HainsworthDepartment of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI.
Raymond G HoffmannDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
Amy L DrendelDepartment of Pediatrics, Medical College of Wisconsin, Milwaukee, WI.
Medical College of Wisconsin · US

Funding

Clinical and Translational Science AwardUL1TR001436 · NCATS · MEDICAL COLLEGE OF WISCONSIN · PI FREED, JULIE K · 2015 to 2025
$47.5M
NCATS NIH HHS UL1 TR001436
6 · The paper itself

Abstract

objectiveThe purpose of this study was to determine the proportion of children undergoing procedural sedation for fracture reduction in the emergency department (ED) observed to experience negative postdischarge behaviors. Predictors of negative behaviors were evaluated, including anxiety.

methodsThis was a prospective cohort study of children receiving intravenous ketamine sedation for ED fracture reduction. The child's anxiety prior to sedation was measured with the Modified Yale Preoperative Anxiety Scale. Negative behavioral changes were measured with the Post-Hospitalization Behavior Questionnaire 1 to 2 weeks after discharge. Descriptive statistics and odds ratios (ORs) were calculated. Chi-square test was used for comparisons between groups. Multivariable logistic regression models evaluated predictors of negative behavioral change after discharge.

resultsNinety-seven patients were enrolled; 82 (85%) completed follow-up. Overall, 33 (40%) children were observed to be highly anxious presedation and 18 (22%) had significant negative behavior changes after ED discharge. Independent predictors for negative behaviors were high anxiety (OR = 9.0, 95% confidence interval [CI] = 2.3-35.7) and nonwhite race (OR = 6.5, 95% CI = 1.7-25.0).

conclusionFor children undergoing procedural sedation in the ED, two in five children have high preprocedure anxiety and almost one in four have significant negative behaviors 1 to 2 weeks after discharge. Highly anxious and nonwhite children have increased risk of negative behavioral changes that have not been previously recognized in the ED setting.

Indexed as

Child BehaviorAnesthetics, DissociativeAnxietyChildChild, PreschoolChi-Square DistributionEmergency Service, HospitalFemaleFracture FixationHumansKetamineLogistic ModelsMaleProcedural SedationProspective StudiesSurveys and QuestionnairesAnesthetics, DissociativeKetamine

Identifiers

PMID28992364
PMCPMC5842101
OpenAlexW2761353208

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.